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Overexpression of Galnt3 in chondrocytes resulted in dwarfism due to the incr...

Yoshida(Carolina Andrea),Kawane(Tetsuya),M... J Biol Chem 2015-02-02

...Col2a1 promoter-enhancer. Galnt3(-/-) mice showed a delay in endochondral ossification and shortened limbs at embryonic ...

Identification of a novel COL2A1 mutation (c.1744G>A) in a Japanese family: a...

Kishiya(Masaki),Nakamura(Yoshihide),Ohishi... J Med Case Rep 2015-05-15

...COL2A1) have been found to affect the entire skeletal system. Recently, inheritable skeletal dysplasia caused by novel C...

Analyses on the mechanisms that underlie the chondroprotective properties of ...

Greco(Karin V),Nalesso(Giovanna),Kaneva(Ma... Biochem Pharmacol 2015-04-28

...COL2A1 and NFAT transcription factors.,CT (10(-10)-10(-8)nM) induced significant up-regulation of cartilage phenotypic m...

Calcitonin treatment is associated with less severe osteoarthritis and reduce...

Li(Jian),Xie(Zong-Gang),Xie(Ye),Dong(Qi-Rong) J Orthop Sci 2015-08-04

...Col2a1, ACAN, Tlr2, Tlr3, and Tlr4.,Signs of osteoarthritis were less severe in rats treated with calcitonin. In the sur...

Modeling type II collagenopathy skeletal dysplasia by directed conversion and...

Okada(Minoru),Ikegawa(Shiro),Morioka(Miho)... Hum Mol Genet 2015-09-23

Type II collagen is a major component of cartilage. Heterozygous mutations in the type II collagen gene (COL2A1) result ...

Hinokitiol reduces matrix metalloproteinase expression by inhibiting Wnt/β-Ca...

Li(Jin),Zhou(Xin-die),Yang(Kong-he),Fan(Te... Int Immunopharmacol 2015-08-25

...Col2a1) and β-catenin expressions in rat chondrocytes induced by interleukin-1β and in an experimental rat model induced...

Characterization of zebrafish Pax1b and Pax9 in fin bud development.

Chen(Xuemei),Huang(Huizhe),Wang(Hua),Guo(F... Biomed Res Int 2015-06-29

...col2a1, Uncx4.1, Noggin3, and aggrecan, confirming the role of Pax1b in chondrocyte differentiation and bone maturation....

All-trans-retinoid acid (ATRA) suppresses chondrogenesis of rat primary hind ...

Wang(Yun-Guo),Xie(Peng),Wang(Yun-Gong),Li(... Environ Toxicol Pharmacol 2015-06-23

...Col2a1 and p63 in rat hind limb bud cells. Limb buds were isolated from embryos from euthanized female rats. Growth of h...

A genetic pedigree analysis to identify gene mutations involved in femoral he...

Wang(Lin),Pan(Hehai),Zhu(Zhen-An) Mol Med Rep 2015-05-22

...COL2A1 gene of the proband; the clinical manifestations of the proband meet the criteria for osteonecrosis. The exons of...

Association of reduced type IX collagen gene expression in human osteoarthrit...

Imagawa(Kei),de Andrés(María C),Hashimoto(... Arthritis Rheumatol 2015-02-10

...COL2A1 enhancer and COL9A1 promoter.,Expression levels were determined using quantitative reverse transcription-polymera...

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