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The competitive nature of HOXB4-transduced HSC is limited by PBX1: the generati…

Krosl(Jana),Beslu(Nathalie),Mayotte(Nadine),… Immunity 2003-05-08

...PBX1 (PBX1(K.D.)) in HOXB4 overexpressing cells, we now present the possibility of generating HSCs that are >20-times mo...

Agenesis of human pancreas due to decreased half-life of insulin promoter facto…

Schwitzgebel(Valerie M),Mamin(Aline),Brun(Th… J Clin Endocrinol Metab 2003-10-10

...Pbx1, or the heterodimer E47-beta 2 was reduced, findings accounted for by decreased IPF1 steady state levels and not by...

Concurrent methylation of multiple genes in childhood ALL: Correlation with phe…

Gutierrez(M I),Siraj(A K),Bhargava(M),Ozbek(… Leukemia 2003-10-21

...PBX1 or MLL-AF4). We determined that children >/=10 years old and children presenting with high WBC (>/=50 x 10(9)/l) bo...

Characterization of PREP2, a paralog of PREP1, which defines a novel sub-family…

Fognani(C),Kilstrup-Nielsen(C),Berthelsen(J)… Nucleic Acids Res 2002-05-13

...PBX1 appears to be essential for nuclear localization of both PREP2 and PBX1. A comparison between the functional proper...

[PCR amplification and cloning of the specific region of the gene encoding 83kd…

Bao(L),Xie(Y) Hua Xi Yi Ke Da Xue Xue Bao 2002-12-11

...pBX1 by cloning the gene fragment into plasmid vector pBK-CMV. The recombinant plasmid can be made into nucleic acid pro...

Real-time reverse transcription polymerase chain reaction detection and quantif…

Curry(J D),Glaser(M C),Smith(M T) Br J Haematol 2002-03-06

...PBX1 fusion gene transcripts associated with t(1;19). The method was highly reproducible and offered exceptional sensiti...

Differential expression of Hox, Meis1, and Pbx1 genes in primitive cells throug…

Pineault(Nicolas),Helgason(Cheryl D),Lawrenc… Exp Hematol 2002-02-21

...Pbx1 and Meis1, at different stages of murine hematopoiesis.,Functionally distinct subpopulations of murine bone marrow ...

Xpbx1b and Xmeis1b play a collaborative role in hindbrain and neural crest gene…

Maeda(Ryu),Ishimura(Akihiko),Mood(Kathleen),… Proc Natl Acad Sci U S A 2002-06-14

...Pbx1b homeodomain protein was isolated and shown to be expressed throughout embryogenesis. Xpbx1b expression overlaps wi...

Pbx1 inactivation disrupts pancreas development and in Ipf1-deficient mice prom…

Kim(Seung K),Selleri(Licia),Lee(Joon S),Zhan… Nat Genet 2002-05-02

...Pbx1 expression, and morphogenesis, cell differentiation and function in mice deficient for Pbx1. Pbx1-/- embryos had pa...

Functional characterization of multiple domains involved in the subcellular loc…

Abramovich(Carolina),Chavez(Elizabeth A),Lan… Oncogene 2002-10-18

...Pbx1. HPIP is expressed in early hematopoietic precursors, can bind all members of the Pbx family and can inhibit the tr...

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