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DrugAppy - An end-to-end deep learning framework for computational drug discove…

Poyatos-Racionero(E),Paniagua-Herranz(L),Pri… Comput Biol Med 2025-11-00

...TEAD4, a compound was identified that outperforms the activity of IK-930, the reference inhibitor for this target. In th...

The Hippo effector TAZ promotes cancer stemness by transcriptional activation o…

Li(J),Li(Z),Wu(Y),Wang(Y),Wang(D),Zhang(W),Y… Cell Death Dis 2019-00-09

...TEAD4 was recruited to two binding sites in SOX2 promoter, which in turn facilitated transcription of SOX2 in HNSCC cell...

The DNA Minor Groove Binders Trabectedin and Lurbinectedin Are Potent Antitumor…

Gäbele(E),Gigante(I),Pastore(M),Cigliano(A),… Int J Mol Sci 2025-09-18

...TEAD4), and cluster of differentiation 7 (CD7) proto-oncogenes. Furthermore, LUR significantly restrained the in vivo gr...

[Prediction of Molecular Signature, Potential Biomarkers, and Molecular Pathway…

Taherkhani(A),Kalantari(S),Nafar(M) Rev Invest Clin 2018-00-00

...TEAD4 and FOXA1 were identified as the regulatory master molecules. LRP1 and ITGA3 were identified as the important targ...

Reprogramming of Extraembryonic Trophoblast Stem Cells into Embryonic Pluripote…

Hong(YJ),Hong(K),Byun(S),Choi(HW),Do(JT) Stem Cells Dev 2018-00-01

...Tead4, trophoblast lineage markers, was diminished. Moreover, these cells developed into three germ layers similarly to ...

Hsa_circ_0091074 regulates TAZ expression via microRNA‑1297 in triple negative …

Hu(J),Ji(C),Hua(K),Wang(X),Deng(X),Li(J),Gra… Int J Oncol 2020-00-00

...TEAD4 axis may represent a potential therapeutic target for triple negative breast cancer in the future.

The nucleolar protein NOP2 is required for nucleolar maturation and ribosome bi…

Wang(H),Wang(L),Wang(Z),Dang(Y),Shi(Y),Zhao(… FASEB J 2020-00-00

...TEAD4) (trophectoderm-specific), tir na nog (NANOG), and kruppel-like factor 4 (KLF4) (inner cell mass-specific). Import...

Dissecting the Gene Expression Networks Associated with Variations in the Major…

Zappaterra(M),Gioiosa(S),Chillemi(G),Zambone… Animals (Basel) 2021-02-27

...TEAD4, a gene regulating mitochondrial activity that seems to be a promising candidate for further studies. On the other...

Transcatheter arterial chemoembolization combined with Hippo/YAP inhibition sig…

Quan(Y),Li(Z),Zhu(K),Liang(J) Lipids Health Dis 2021-07-25

...TEAD4. TACE plus verteporfin significantly enhanced the downregulation of effectors in the Hippo/YAP signaling pathway a...

Importance of methionine metabolism in morula-to-blastocyst transition in bovin…

Ikeda(S),Sugimoto(M),Kume(S) J Reprod Dev 2012-00-00

...TEAD4 were increased by ethionine treatment relative to the control (P<0.01). Furthermore, immunofluorescence analysis o...

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