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TEL/AML1 rearrangement and the prognostic significance in childhood acute lymph…

Tsang(K S),Li(C K),Chik(K W),Shing(M M),Tsoi… Am J Hematol 2001-10-18

...PBX1, MLL/AF4, and BCR/ABL were not found in TEL/AML1+ patients. Coexpression of cross-lineage antigens was associated w...

Clearance of maternal leukaemic cells in a neonate.

van der Velden(V H),Willemse(M J),Mulder(M F… Br J Haematol 2001-08-16

...PBX1 fusion gene transcript. In the cord blood sample, a tumour load of approximately 4 x 10(-4) was found, whereas all ...

The Hox cofactor and proto-oncogene Pbx1 is required for maintenance of definit…

DiMartino(J F),Selleri(L),Traver(D),Firpo(M … Blood 2001-09-13

Pbx1 is the product of a proto-oncogene originally discovered at the site of chromosomal translocations in acute leukemi...

HoxB8 requires its Pbx-interaction motif to block differentiation of primary my…

Knoepfler(P S),Sykes(D B),Pasillas(M),Kamps(… Oncogene 2001-10-11

...Pbx1, an oncogenic derivative of Pbx1, both retains its ability to heterodimerize with Hox proteins and arrest myeloid d...

Estrogen-dependent E2a/Pbx1 myeloid cell lines exhibit conditional differentiat…

Sykes(D B),Kamps(M P) Blood 2001-12-05

...Pbx1-estrogen receptor fusion protein. Clones were identified that proliferated as immortalized blasts in the presence o...

Novel alternative PBX3 isoforms in leukemia cells with distinct interaction spe…

Milech(N),Kees(U R),Watt(P M) Genes Chromosomes Cancer 2001-12-05

...PBX1. While the expression pattern of PBX1 is restricted, PBX2 and PBX3 are ubiquitously expressed. Little is known abou...

Requirement for Pbx1 in skeletal patterning and programming chondrocyte prolife…

Selleri(L),Depew(M J),Jacobs(Y),Chanda(S K),… Development 2001-12-04

...Pbx1 contributions were investigated through characterization of Pbx1-deficient mice. Pbx1 mutants died at embryonic day...

Defining roles for HOX and MEIS1 genes in induction of acute myeloid leukemia.

Thorsteinsdottir(U),Kroon(E),Jerome(L),Blasi… Mol Cell Biol 2001-01-18

...PBX1, in generating AML. In addition, we show that the HOXA9 and HOXB3 genes play key roles in establishing all the main...

Detection of E2A translocations in leukemias via fluorescence in situ hybridiza…

Boomer(T),Varella-Garcia(M),McGavran(L),Melt… Leukemia 2001-03-29

...PBX1, t(17;19)(q22;p13) and E2A-HLF and a cryptic inv(19)(p13;q13) and E2A-FB1. While E2A is fused to PBX1 in most ALLs ...

The leukemogenic transcription factor E2a-Pbx1 induces expression of the putati…

Rutherford(M N),Bayly(G R),Matthews(B P),Oku… Leukemia 2001-03-29

...Pbx1 in the interleukin-3 (IL-3) dependent, bone marrow-derived cell line Ba/F3. We show that forced expression of E2a-P...

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