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Requirement for Pbx1 in skeletal patterning and programming chondrocyte prolife…

Selleri(L),Depew(M J),Jacobs(Y),Chanda(S K),… Development 2001-12-04

...Pbx1 contributions were investigated through characterization of Pbx1-deficient mice. Pbx1 mutants died at embryonic day...

Novel alternative PBX3 isoforms in leukemia cells with distinct interaction spe…

Milech(N),Kees(U R),Watt(P M) Genes Chromosomes Cancer 2001-12-05

...PBX1. While the expression pattern of PBX1 is restricted, PBX2 and PBX3 are ubiquitously expressed. Little is known abou...

Estrogen-dependent E2a/Pbx1 myeloid cell lines exhibit conditional differentiat…

Sykes(D B),Kamps(M P) Blood 2001-12-05

...Pbx1-estrogen receptor fusion protein. Clones were identified that proliferated as immortalized blasts in the presence o...

Cell signaling switches HOX-PBX complexes from repressors to activators of tran…

Saleh(M),Rambaldi(I),Yang(X J),Featherstone(… Mol Cell Biol 2000-12-19

...PBX1A. We map a site of interaction with HDAC1 to the PBX1 N terminus and show that the PBX partner is required for repr...

p21 is a transcriptional target of HOXA10 in differentiating myelomonocytic cel…

Bromleigh(V C),Freedman(L P) Genes Dev 2000-11-29

...PBX1 and MEIS1, activate p21 transcription, resulting in cell cycle arrest and differentiation. These experiments for th...

The incidence of clonal T-cell receptor rearrangements in B-cell precursor acut…

Brumpt(C),Delabesse(E),Beldjord(K),Davi(F),C… Blood 2000-10-04

...PBX1). In contrast, TCRG rearrangements, which occur in 60% of patients overall, are frequent in BCR-ABL and TEL-AML1, a...

[The genetic diagnosis of hematopoietic malignancy by polymerase chain reaction…

Yokota(H),Kitamura(K) Rinsho Byori 2000-12-20

...PBX1, TEL/AML1, and MLL/LTG4 by reverse transcription-nested-polymerase chain reaction (RT-nested-PCR) have been routine...

A conformational change in PBX1A is necessary for its nuclear localization.

Saleh(M),Huang(H),Green(N C),Featherstone(M … Exp Cell Res 2000-11-13

...PBX1A HD abolishes interactions with MEIS/PREP but allows nuclear accumulation of PBX1A. We use deletion mapping and fus...

A carboxy-terminal deletion mutant of Notch1 accelerates lymphoid oncogenesis i…

Feldman(B J),Hampton(T),Cleary(M L) Blood 2000-10-18

...PBX1 and Notch1(DeltaC) genes displayed a substantially shortened latency for tumor development compared with E2A-PBX1 s...

Role for homodimerization in growth deregulation by E2a fusion proteins.

Bayly(R),LeBrun(D P) Mol Cell Biol 2000-08-28

...Pbx1 incorporates transcriptional activation domains from E2a and a DNA-binding homeodomain from Pbx1 inspired a model i...

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