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Lineage segregation in human pre-implantation embryos is specified by YAP1 and …

Regin(M),Essahib(W),Demtschenko(A),Dewandre(… Hum Reprod 2023-00-01

...TEAD4/YAP1 activity that upregulates Cdx2 and Gata3 expression while inner cells exclude YAP1 which upregulates Sox2 exp...

Targeting the YAP/TAZ Pathway in Uveal and Conjunctival Melanoma With Verteporf…

Brouwer(NJ),Konstantinou(EK),Gragoudas(ES),M… Invest Ophthalmol Vis Sci 2021-00-01

...TEAD4 was increased in cases with M3/BAP1-loss (P = 0.002 and P = 0.006) and related to metastasis (P = 0.004). UM cell ...

Gene Expression Pattern of Peyer's Patch Lymphocytes Exposed to Kagocel Suggest…

Andreev-Andrievskiy(AA),Zinovkin(RA),Mashkin… Front Pharmacol 2021-00-00

...Tead4, and ZSCAN) and master-regulators has been identified (cIAP, CIKS, dock9, MEKK1, FXR, IKK, IRAK, TRAF, dsRNA:TLR3:...

Transcriptional and histopathological profiling of skeletal muscle in Bla/J mic…

Limaev(IS),Gladyshev(NS),Yakovlev(IA),Shigap… Biol Open 2026-09-15

...Tead4 suppression, pointing to an early failure of the reparative program. Exploratory RNA sequencing also identified a ...

YAP ISGylation increases its stability and promotes its positive regulation on …

Xue(X),Tian(X),Zhang(C),Miao(Y),Wang(Y),Peng… Cell Death Discov 2022-02-11

...TEAD4) binding to the 6PGL promoter to activate PPP. In clinical lung adenocarcinoma (LUAD) specimens, we found that YAP...

PAF1 cooperates with YAP1 in metaplastic ducts to promote pancreatic cancer.

Nimmakayala(RK),Ogunleye(AO),Parte(S),Krishn… Cell Death Dis 2022-00-01

...TEAD4, and SOX9 and decreased colony formation and stemness in KC and PC cells. CA3 treatment also reduced the viability...

NR5A2 connects zygotic genome activation to the first lineage segregation in to…

Lai(F),Li(L),Hu(X),Liu(B),Zhu(Z),Liu(L),Fan(… Cell Res 2023-00-00

...Tead4 and Gata3 at the 8C stage. By contrast, master pluripotency TFs NANOG, SOX2, and OCT4 targeted both early and late...

Transient heat stress irreversibly disrupts molecular signals, cellular and dev…

Singh(D),Sarwalia(P),Kumar(M),Gohain(M),Jain… Mol Biol Rep 2026-03-26

...TEAD4, CDX2, ZO-1, ETS2 and NKB1 was implicated in cellular damage, inconsistent and embryonic development, consequently...

YAP Orchestrates Heterotypic Endothelial Cell Communication via HGF/c-MET Signa…

Thomann(S),Weiler(SME),Marquard(S),Rose(F),B… Cancer Res 2020-00-15

...TEAD4)-dependent transcriptional induction of osteopontin (Opn) stimulated c-Met expression in EC with CEC phenotype, wh...

Dickkopf-1 promotes Vascular Smooth Muscle Cell proliferation and migration thr…

Zheng(TF),Liu(XL),Li(X),Wang(QQ),Zhao(YC),Li… Int J Biol Sci 2021-00-00

...TEAD4 bound directly to the promoter of UHRF1, and blocking the YAP-TEAD interaction inhibited UHRF1 upregulation due to...

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