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Distinct in vivo engraftment and growth patterns of t(1;19)+/E2A-PBX1+ and t(9;…

Waurzyniak(B J),Heerema(N),Sensel(M G),Gayno… Leuk Lymphoma 1999-06-29

...PBX1+ or t(9;22)+/BCR-ABL+ acute lymphoblastic leukemia. Leukemic cells from 13/24 t(1;19)+/E2A-PBX1+ patients caused ov...

NMR studies of the pbx1 TALE homeodomain protein free in solution and bound to …

Jabet(C),Gitti(R),Summers(M F),Wolberger(C) J Mol Biol 1999-10-04

...Pbx1 homeodomain protein. The crystal structure of a human HoxB1-Pbx1-DNA ternary complex revealed that interactions bet...

The subcellular localization of PBX1 and EXD proteins depends on nuclear import…

Berthelsen(J),Kilstrup-Nielsen(C),Blasi(F),M… Genes Dev 1999-06-01

Nuclear localization of the Extradenticle (EXD) and PBX1 proteins is regionally restricted during Drosophila and mammali...

Structure of a HoxB1-Pbx1 heterodimer bound to DNA: role of the hexapeptide and…

Piper(D E),Batchelor(A H),Chang(C P),Cleary(… Cell 1999-03-18

...Pbx1 protein formed in part by a three-amino acid insertion in the Pbx1 homeodomain. The Pbx1 DNA-binding domain is larg...

Conserved regulation of proximodistal limb axis development by Meis1/Hth.

Mercader(N),Leonardo(E),Azpiazu(N),Serrano(A… Nature 1999-12-10

...Pbx1 activity by promoting nuclear import of the Pbx1 protein; and that ectopic expression of Meis1 in chicken and hth i...

Structure of a DNA-bound Ultrabithorax-Extradenticle homeodomain complex.

Passner(J M),Ryoo(H D),Shen(L),Mann(R S),Agg… Nature 1999-03-15

...Pbx1) to affect development along the anterior-posterior axis of animals.

Identification of a novel molecular partner of the E2A gene in childhood leukem…

Brambillasca(F),Mosna(G),Colombo(M),Rivolta(… Leukemia 1999-04-07

...PBX1 and HLF, following two chromosome translocations recurrent in childhood pre-B ALL. We have identified a novel gene,...

Oncogenic homeodomain transcription factor E2A-Pbx1 activates a novel WNT gene …

McWhirter(J R),Neuteboom(S T),Wancewicz(E V)… Proc Natl Acad Sci U S A 1999-10-21

...Pbx1. Here, we show that the E2A-Pbx1 fusion protein activates the expression of a novel WNT gene, WNT-16. WNT-16 normal...

The oncoprotein E2A-Pbx1a collaborates with Hoxa9 to acutely transform primary …

Thorsteinsdottir(U),Krosl(J),Kroon(E),Haman(… Mol Cell Biol 1999-09-10

...Pbx1) and 19 (E2A) leading to the expression of the E2A-Pbx1 fusion oncoprotein occurs in approximately 5 to 10% of acut...

Receptor interacting protein RIP140 inhibits both positive and negative gene re…

Subramaniam(N),Treuter(E),Okret(S) J Biol Chem 1999-07-15

...Pbx1/HOXB1 responsive elements, as well as gene repression through a negative GRE and cross-talk with NF-kappaB (RelA). ...

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