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Structure of a HoxB1-Pbx1 heterodimer bound to DNA: role of the hexapeptide and…

Piper(D E),Batchelor(A H),Chang(C P),Cleary(… Cell 1999-03-18

...Pbx1 protein formed in part by a three-amino acid insertion in the Pbx1 homeodomain. The Pbx1 DNA-binding domain is larg...

Structure of a DNA-bound Ultrabithorax-Extradenticle homeodomain complex.

Passner(J M),Ryoo(H D),Shen(L),Mann(R S),Agg… Nature 1999-03-15

...Pbx1) to affect development along the anterior-posterior axis of animals.

Functional and cooperative interactions between the homeodomain PDX1, Pbx, and …

Goudet(G),Delhalle(S),Biemar(F),Martial(J A)… J Biol Chem 1999-03-11

...Pbx1 and Prep1 proteins bind cooperatively to the UE-A site, whereas neither protein can bind this site alone. Transient...

Sequence and genomic organization of the mouse Lim1 gene.

Li(Y),Cheah(S S),Deng(J M),Shawlot(W),Behrin… Mamm Genome 1999-07-08

...Pbx1 binding sites were also identified. Like most LIM domain encoding genes, the LIM domains of Lim1 are each encoded o...

Pim1 cooperates with E2a-Pbx1 to facilitate the progression of thymic lymphomas…

Feldman(B J),Reid(T R),Cleary(M L) Oncogene 1998-01-08

Mice transgenic for the leukemia oncogene E2A-PBX1 invariably develop lethal, high-grade T-cell lymphomas by 5 months of...

Hyperdiploidy and E2A-PBX1 fusion in an adult with t(1;19)+ acute lymphoblastic…

Hunger(S P),Sun(T),Boswell(A F),Carroll(A J)… Genes Chromosomes Cancer 1998-01-13

...PBX1 fusion mRNAs. A minority of cases are early pre-B (clg-/slg-), do not express the characteristic pattern of cell su...

Meis1 and pKnox1 bind DNA cooperatively with Pbx1 utilizing an interaction surf…

Knoepfler(P S),Calvo(K R),Chen(H),Antonaraki… Proc Natl Acad Sci U S A 1998-02-02

...Pbx1, suggesting that leukemogenesis by E2a-Pbx1 and Hox proteins may alter transcription of cellular genes regulated by...

Fli-1b is generated by usage of differential splicing and alternative promoter.

Dhulipala(P D),Lee(L),Rao(V N),Reddy(E S) Oncogene 1998-11-04

...PBX1, EBP, PEA-3, ETS-2, Sp-1, c-Myc, TBP, GATA-1 and Oct-3 were conserved in the promoter sequence. Functional promoter...

Different patterns of homozygous p16INK4A and p15INK4B deletions in childhood a…

Maloney(K W),McGavran(L),Odom(L F),Hunger(S … Leukemia 1998-09-24

...PBX1 and E2A-HLF, respectively. Previously, a negative association was found between the t(1;19) and homozygous p16/p15 ...

Antagonism between extradenticle function and Hedgehog signalling in the develo…

González-Crespo(S),Abu-Shaar(M),Torres(M),Ma… Nature 1998-07-27

...Pbx1) is regulated at the subcellular level, and that its pattern of nuclear localization in the mouse limb resembles th...

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