Literature Search

Mensah(GAK),Schaefer(KG),Bartlett(MG),Robert… Int J Mol Sci 2023-11-07

...Pgp-mediated transport of xenobiotics. In this study, we investigated the drug-induced conformational changes in Pgp and...

Gaspar(F),Jacost-Descombes(C),Gosselin(P),Re… Clin Pharmacokinet 2025-02-00

...Pgp inhibitors on fexofenadine pharmacokinetics. Age, renal insufficiency, and Pgp inhibitors significantly influenced f...

Wuytack(F),Gutke(A),Stuge(B),Mørkved(S),Olss… BMC Med Res Methodol 2018-00-03

...PGP-COS development process to address these questions. The PGP-COS study will include five phases: (1) A systematic rev...

Sharom(Frances Jane) Front Oncol 2014-06-24

...Pgp function. Recent studies focusing on thermodynamics and kinetics have revealed some important principles governing P...

Yang(R),Chen(Z),Xie(F),Xie(M),Liu(N),Su(Z),G… J Chem Inf Model 2021-00-25

...Pgp) is a main factor contributing to multidrug resistance and the consequent failure of chemotherapy. Overcoming Pgp ef...

Zhang(JT),Duthie(M),Ling(V) J Biol Chem 1993-07-15

P-glycoprotein (Pgp) is a tandemly duplicated plasma membrane protein containing 12 predicted transmembrane (TM) segment...

Hyman(R),Cunningham(K) Immunogenetics 1984-00-00

...Pgp-1 glycoprotein. Hybrids between pseudodiploid lines, in contrast, show extinction of Pgp-1. Thy-1+ or Pgp-1+ reverta...

Minderman(H),Brooks(TA),O'Loughlin(KL),Ojima… Cancer Chemother Pharmacol 2004-05-00

...Pgp-expressing cells by virtue of modulation of Pgp-mediated transport. The synthetic taxane tRA96023 also modulates Pgp...

Bankstahl(Jens P),Hoffmann(Katrin),Bethmann(… Neuropharmacology 2008-07-22

...Pgp) at the blood-brain barrier. Increased expression of Pgp has been determined both in epileptogenic brain tissue of p...

de Vries(Erik F J),Doorduin(Janine),Vellinga… Nucl Med Biol 2008-09-05

...Pgp substrates. To clarify whether Pgp is involved in the sensitizing effect of celecoxib, we investigated in vivo wheth...