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A role for synaptotagmin (p65) in regulated exocytosis.

Elferink(L A),Peterson(M R),Scheller(R H) Cell 1993-02-24

...rab3A, synaptophysin, synaptotagmin, and SV2, were used to investigate their function. Microinjection of monoclonal and ...

Mutants of Rab3A analogous to oncogenic Ras mutants. Sensitivity to Rab3A-GTP...

Brondyk(W H),McKiernan(C J),Burstein(E S),... J Biol Chem 1993-06-04

...Rab3A-GAP and insensitive to Rab3A-GRF. Q81L-Rab3A and wild-type Rab3A that were bound to a nonhydrolyzable GTP analog h...

Inhibition of Rab3B expression attenuates Ca(2+)-dependent exocytosis in rat ...

Lledo(P M),Vernier(P),Vincent(J D),Mason(W... Nature 1993-08-26

...Rab3A, B, C and D) are thought to be associated with membrane vesicles or granules undergoing exocytotic fusion with the...

Identification of small GTP-binding rab proteins in human platelets: thrombin...

Karniguian(A),Zahraoui(A),Tavitian(A) Proc Natl Acad Sci U S A 1993-09-23

...rab3A protein, were present in platelets and in endothelial cells. To probe their functional significance in platelets, ...

Characterization of a guanine nucleotide dissociation stimulator for a ras-re...

Albright(C F),Giddings(B W),Liu(J),Vito(M)... EMBO J 1993-03-10

...rab3a and ypt1). While the ralGDS protein is phosphorylated on serine residues, we find no evidence that phosphorylation...

Rab effector domain peptides stimulate the release of neurotransmitter from c...

Richmond(J),Haydon(P G) FEBS Lett 1993-08-10

The involvement of the small GTP-binding protein rab3A in synaptic transmission was tested by presynaptic microinjection...

Rab GDP dissociation inhibitor as a general regulator for the membrane associ...

Ullrich(O),Stenmark(H),Alexandrov(K),Huber... J Biol Chem 1993-09-16

...rab3A GDI, a cytosolic protein which inhibits the dissociation of GDP from smg p25A/rab3A, Sec4p, and rab11, has also be...

Accumulation of mRNAs encoding synaptic vesicle-specific proteins precedes ne...

Marazzi(G),Buckley(K M) Dev Dyn 1993-12-22

...rab3a), using in situ hybridization to mouse embryonic tissue sections. Our results indicate that transcription of these...

DSS4-1 is a dominant suppressor of sec4-8 that encodes a nucleotide exchange ...

Moya(M),Roberts(D),Novick(P) Nature 1993-03-08

...Rab3A GDP dissociation stimulating activity has been presented. We report here the use of suppressor analysis to clone a...

A mammalian guanine-nucleotide-releasing protein enhances function of yeast s...

Burton(J),Roberts(D),Montaldi(M),Novick(P)... Nature 1993-03-08

...Rab3a, but not from Ras2. Mss4 shows sequence similarity to Dss4, a yeast protein with similar biochemical properties.

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