...CSF1, and with TReg cells through APP, ANGPTL4, and SIGLEC9 signaling. Considering the clinical relevance of macrophages...
...CSF1-producing malignant cells and SPP1+ macrophages. Experimentally, malignant cell-derived CSF1 induced SPP1+ macropha...
...CSF1R (CD115), the receptor for lineage-specific growth factors CSF1 and IL-34. Here, we report that acute CSF1R blockad...
...CSF1, AQP9, FLNB, COL7A1, and MXI1 was established. In GSE14520, the signature predicted poor OS (HR = 1.94, 95% CI: 1.4...
...Csf1 expression, consistent with a model where excess leak results in annexins A1 and A2 in the ECM, where this protein ...
...Csf1, Il-34, Igf1, Igfbp5, Tgfβ4 (Tgfβ1 in mammals), P75NTR/ Tnfrsf16, Hgf, Vegfa, that presumably stabilizes the macrop...
...CSF1-CSF1R core signaling axes, and the regulation of TAMs' functional polarization by hypoxia and metabolic reprogrammi...
...CSF1/CSF1R blockade) to inhibition of monocyte recruitment (CCL2/CCR2 axis), functional reprogramming (CD40 agonism, PI3...
...CSF1-CSF1R axis. Spatial analyses demonstrated enrichment of SehighMali cells in tumor cores and close colocalization wi...
...CSF1 signaling, thereby fostering an immunologically "cold" tumor and conferring resistance to anti-PD-1 therapy. RAD21 ...
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