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Explainable machine learning-guided integrated multiomics analysis reveals ma...

Azimzade(Y),Haugen(MH),Kristensen(VN),Frig... Nat Commun 2026-05-25

...CSF1, and with TReg cells through APP, ANGPTL4, and SIGLEC9 signaling. Considering the clinical relevance of macrophages...

The CSF1+ tumor cell-SPP1+ macrophage axis drives gastric cancer progression ...

Zhang(H),You(Y),Peng(J),Du(Q),Liu(X) Front Immunol None

...CSF1-producing malignant cells and SPP1+ macrophages. Experimentally, malignant cell-derived CSF1 induced SPP1+ macropha...

CSF1R regulates monocyte subset differentiation and intracellular metabolism.

Gallerand(A),Merlin(J),Caillot(Z),Delaby(C... Nat Commun 2026-07-04

...CSF1R (CD115), the receptor for lineage-specific growth factors CSF1 and IL-34. Here, we report that acute CSF1R blockad...

Development and Validation of a Six-Gene Signature of Myeloid Antigen Present...

Tan(Y),Xiang(J),Wang(Z),Wang(Y),Chen(A),Wu(Q) Cancer Inform None

...CSF1, AQP9, FLNB, COL7A1, and MXI1 was established. In GSE14520, the signature predicted poor OS (HR = 1.94, 95% CI: 1.4...

Excess muscle plasma membrane leak disrupts ECM content and shifts macrophage...

Lee(G),Fitt(AJ),Long(AM),Vaught(LA),DeBias... JCI Insight 2026-08-10

...Csf1 expression, consistent with a model where excess leak results in annexins A1 and A2 in the ECM, where this protein ...

Traffic and functional polarization of macrophages in the areas of programmed...

Moran(G),Duarte-Olivenza(C),Hurle(JM),Lord... Apoptosis 2026-03-07

...Csf1, Il-34, Igf1, Igfbp5, Tgfβ4 (Tgfβ1 in mammals), P75NTR/ Tnfrsf16, Hgf, Vegfa, that presumably stabilizes the macrop...

TAMs in the Gynecological Tumor Microenvironment: Insights from Cross-Cancer ...

Li(R),Liang(H),Chen(H),Weng(R),Ding(Q),Cai... Cancers (Basel) 2026-04-25

...CSF1-CSF1R core signaling axes, and the regulation of TAMs' functional polarization by hypoxia and metabolic reprogrammi...

Tumor-Associated Macrophages (TAMs) in Cancer: Functional Programs, Metastati...

Ono(K),Momen-Heravi(F) Cancers (Basel) 2026-04-29

...CSF1/CSF1R blockade) to inhibition of monocyte recruitment (CCL2/CCR2 axis), functional reprogramming (CD40 agonism, PI3...

Single-Cell and Spatial Transcriptomics Reveals Selenoproteins Shape Immunosu...

Zhang(X),Zhang(N),Zhong(Y),Ou(S),Wu(G),Ouy... Cancers (Basel) 2026-05-06

...CSF1-CSF1R axis. Spatial analyses demonstrated enrichment of SehighMali cells in tumor cores and close colocalization wi...

RAD21 drives tumor progression and confers anti-PD-1 resistance by reprogramm...

Cai(W),Xiao(C),Xin(Y),Wang(D),Deng(Z),Liu(... Cancer Lett 2026-10-01

...CSF1 signaling, thereby fostering an immunologically "cold" tumor and conferring resistance to anti-PD-1 therapy. RAD21 ...

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