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Accumulation of GABAergic neurons, causing a focal ambient GABA gradient, and...

Wang(Tianying),Kumada(Tatsuro),Morishima(T... Cereb Cortex 2014-10-29

...Cux1-positive pyramidal neurons outlined the GABAergic neurons and were absent from the superficial layer, forming cell-...

Identification of fat mass and obesity associated (FTO) protein expression in...

Gan(Xiaohong Tracey),Zhao(Ganjian),Huang(C... PLoS One 2014-05-16

...CUX1 isoform whereas the longer p200CUX1 protein was not significantly affected. Cathepsin L expression and activity wer...

The effect of hypothermia therapy on cortical laminar disruption following is...

Kida(Hiroyuki),Nomura(Sadahiro),Shinoyama(... PLoS One 2014-03-27

...Cux1/Ctip2); the number of neurons was counted; and the expression of myelin basic protein (MBP) was determined. The hyp...

RAS transformation requires CUX1-dependent repair of oxidative DNA damage.

Ramdzan(Zubaidah M),Vadnais(Charles),Pal(R... PLoS Biol 2014-11-07

...CUX1 expression facilitates tumor development while increased CUX1 expression is needed in tumorigenic cells. Indeed, CU...

A single-tube multiplexed assay for detecting ALK, ROS1, and RET fusions in l...

Lira(Maruja E),Choi(Yoon-La),Lim(Sun Min),... J Mol Diagn 2014-10-28

...CUX1), yielding an in-frame CUX1-RET fusion. ROS1 and RET fusions were significantly enriched in tumors without KRAS/EGF...

Culturing layer-specific neocortical neurons as a cell replacement therapy fo...

Cramer(Nathan Peter),Chatterjee(Mitali),Li... Front Neurol 2014-01-16

...Cux1, ER81, and RORβ. Future studies will investigate the potential of transplanting layer-specific neurons generated an...

DNA hypermethylation and DNA hypomethylation is present at different loci in ...

Smyth(Laura J),McKay(Gareth J),Maxwell(Ale... Epigenetics 2014-11-14

...CUX1, ELMO1, FKBP5, INHBA-AS1, PTPRN2, and PRKAG2 genes; several genes are differentially methylated in kidney tissue an...

Zbtb20 defines a hippocampal neuronal identity through direct repression of g...

Nielsen(Jakob V),Thomassen(Mads),Møllgård(... Cereb Cortex 2014-11-28

...Cux1, Cux2, Fezf2, Foxp2, Mef2c, Rorb, Satb2, Sox5, Tbr1, Tle4, and Zfpm2. We show that Zbtb20 represses these genes dur...

Hypomorphism for RPGRIP1L, a ciliary gene vicinal to the FTO locus, causes in...

Stratigopoulos(George),Martin Carli(Jayne ... Cell Metab 2014-12-31

...CUX1-regulatory element within the implicated FTO region controls expression of FTO and the nearby ciliary gene, RPGRIP1...

CUX1, a haploinsufficient tumour suppressor gene overexpressed in advanced ca...

Ramdzan(Zubaidah M),Nepveu(Alain) Nat Rev Cancer 2014-11-17

...CUX1 expression promotes tumour development. Paradoxically, increased CUX1 expression is associated with tumour progress...

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