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Expression of the secondary granule proteins major basic protein 1 (MBP-1) an...

Doyle(Alfred D),Jacobsen(Elizabeth A),Ochk... Blood 2013-10-28

...EPX). Unpredictably, a knockout approach targeting the genes encoding these proteins demonstrated that, unlike in mice c...

Homologous recombination into the eosinophil peroxidase locus generates a str...

Doyle(Alfred D),Jacobsen(Elizabeth A),Ochk... J Leukoc Biol 2013-09-05

...Epx. This knock-in strategy overcame previous inefficiencies associated with eosinophil-specific transgenic approaches a...

In vitro Release of Eosinophil Proteins in Allergic and Atopic Dermatitis Pat...

Poulsen(L K),Reimert(C M),Bindslev-Jensen(... Mediators Inflamm 2012-09-10

...EPX) were determined in serum (clotting time = 2.0 h) and plasma. Serum and plasma ECP in normal donors demonstrated lar...

Role of serological markers of activated eosinophils in inflammatory bowel di...

Dainese(Raffaella),Galliani(Ermenegildo A)... Eur J Gastroenterol Hepatol 2012-05-10

...EPX levels (r=0.77; P<0.0001).,Serological ECP and EPX findings did not correlate with IgE hypersensitivity findings or ...

Acetic acid-enhanced chromoendoscopy is more cost-effective than protocol-gui...

Bhandari(P),Kandaswamy(P),Cowlishaw(D),Lon... Dis Esophagus 2012-12-05

...EPX-4400 processor were used. Inspection of Barrett's neoplasia was carried out using white light followed by AA. Neopla...

The development of a sensitive and specific ELISA for mouse eosinophil peroxi...

Ochkur(Sergei I),Kim(John Dongil),Prothero... J Immunol Methods 2012-05-21

...EPX). This strategy identified unique pairs of antibodies with high avidity to the target protein and led to the develop...

A sensitive high throughput ELISA for human eosinophil peroxidase: a specific...

Ochkur(Sergei I),Kim(John Dongil),Prothero... J Immunol Methods 2012-12-07

...EPX) were used to develop an eosinophil-specific and sensitive sandwich ELISA. The sensitivity of this EPX-based ELISA w...

Biomarkers of disease and treatment in murine and cynomolgus models of chroni...

Louten(Jennifer),Mattson(Jeanine D),Malina... Biomark Insights 2012-08-23

...Epx, Mmp12, and Klk1 were good indicators of early therapeutic intervention. In NHP, AMCase, sICAM-1, CLCA1, and GP-39 w...

Fundamental reaction pathway and free energy profile for inhibition of protea...

Wei(Donghui),Lei(Beilei),Tang(Mingsheng),Z... J Am Chem Soc 2012-11-05

...EPX by the negatively charged Thr1-O(γ) atom, followed by a proton transfer from Thr1-N(z) to the carbonyl oxygen of EPX...

Fecal eosinophil cationic protein as a marker of active disease and treatment...

Wagner(Michael),Peterson(Christer G B),Sto... Scand J Gastroenterol 2012-01-05

...EPX, F-MPO and FC levels, respectively. All markers decreased during the treatment, particularly F-ECP and F-EPX, which ...

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