Yamamoto(Hiroyuki),Watanabe(Yoshiyuki),Mae... World J Gastroenterol 2015-04-13

...FAT4, a member of the cadherin gene family. Mutations in chromatin remodeling genes (ARID1A, MLL3 and MLL) have been fou...

Yu(Jun),Wu(William K K),Li(Xiangchun),He(J... Gut 2015-05-18

...FAT4 and DOCK2), exhibited high mutation prevalence (6-14% for novel cancer genes) and higher-than-expected number of no...

Murphy(Andrew J),Pierce(Janene),de Caestec... Pediatr Blood Cancer 2014-02-25

The Yes-associated-protein-1 (YAP1) is a novel, direct regulator of stem cell genes both in development and cancer. FAT4...

Cappello(Silvia),Gray(Mary J),Badouel(Caro... Nat Genet 2014-01-08

...FAT4 lead to a recessive syndrome in humans that includes periventricular neuronal heterotopia. Reducing the expression ...

Wadhwa(Roopma),Song(Shumei),Lee(Ju-Seog),Y... Nat Rev Clin Oncol 2014-06-26

...FAT4, MLL and KMT2C) have also been identified and are of interest. Variations in the therapeutic approaches dependent o...

Tenedini(E),Bernardis(I),Artusi(V),Artuso(... Leukemia 2014-07-10

...FAT4, DAP3, POLG and NRAS), we demonstrated a mutation frequency between 3 and 8%. We also found that mutations at codon...

Bossuyt(W),Chen(C-L),Chen(Q),Sudol(M),McNe... Oncogene 2014-04-29

...Fat4 cadherin, the ortholog of the Hippo pathway regulator Fat in Drosophila, does not apparently regulate the Hippo pat...

Sadeqzadeh(Elham),de Bock(Charles E),Thorn... Med Res Rev 2014-07-28

The vertebrate Fat cadherins comprise a small gene family of four members, Fat1-Fat4, all closely related in structure t...

Gao(Yi-Bo),Chen(Zhao-Li),Li(Jia-Gen),Hu(Xu... Nat Genet 2014-12-15

...FAT4 (27%) or AJUBA (JUB; 7%) and NOTCH1, NOTCH2 or NOTCH3 (22%) or FBXW7 (5%), respectively. These results define the m...

Alders(Mariëlle),Al-Gazali(Lihadh),Cordeir... Hum Genet 2014-10-07

...FAT4 gene. Subsequent targeted mutation analysis of FAT4 in a cohort of 24 CCBE1 mutation-negative Hennekam syndrome pat...