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[Sustained hematologic response in chronic eosinophilic leukemia with low dos...

Torres C(Demetrio),Chandía(Mauricio) Rev Med Chil 2015-04-08

...FIP1L1/PDGFRA. Imatinib therapy was initiated, resulting in a rapid and progressive reduction in the absolute eosinophil...

A study of genes involved in adipocyte differentiation.

Zhu(Shunming),Cheng(Gong),Zhu(Huolan),Guan... J Pediatr Endocrinol Metab 2015-09-22

...FIP1L1, MAP3K2 and PEX14. Furthermore, genes involved in lipid metabolism, signal transduction, DNA replication, redox s...

Murine models of eosinophilic leukemia: a model of FIP1L1-PDGFRα initiated ch...

Yamada(Yoshiyuki),Cancelas(Jose A),Rothenb... Methods Mol Biol 2015-02-19

...FIP1L1-PDGFRα (F/P) fusion tyrosine kinase was identified in patients with HES and found to be the most common clonal de...

Antitumor activity of S116836, a novel tyrosine kinase inhibitor, against ima...

Shen(Yingying),Ren(Xiaomei),Ding(Ke),Zhang... Oncotarget 2015-07-30

The FIP1-like-1-platelet-derived growth factor receptor alpha (FIP1L1-PDGFRα) fusion oncogene is the driver factor in a ...

The lymphoid variant of hypereosinophilic syndrome: study of 21 patients with...

Lefèvre(Guillaume),Copin(Marie-Christine),... Medicine (Baltimore) 2015-01-26

...FIP1L1-PDGFRA chronic eosinophilic leukemia patients, CS are always effective in these patients, but CS-sparing treatmen...

CD30+ clonal T-cell lymphoid proliferation of the skin in a patient with hype...

Kempf(Werner),Kazakov(Dmitry V),Szep(Zolta... J Cutan Pathol 2015-09-29

...FIP1L1-PDGFRA, PDGFRB or FGFR1 were found. The skin lesions showed transient response to systemic and topical corticoste...

Complete and long-lasting cytologic and molecular remission of FIP1L1-PDGFRA-...

Barraco(Daniela),Carobolante(Francesca),Ca... Eur J Haematol 2015-01-06

...FIP1L1-PDGFRA-positive chronic myeloproliferative disorders with eosinophilia. However, the coexistence of FIP1L1-PDGFRA...

[Detecting the abnormal expression of PDGFRA gene in eosinophilia by FISH].

Wang(Yan-Fang),Xi(Lian-Yong),Wang(Hua),Don... Zhongguo Shi Yan Xue Ye Xue... 2015-03-30

...FIP1L1-PDGFRA (F/P) was found in 2 patients and the positive rate of F/P fusion gene detected by probe 4q12 was 17% in t...

The conformational control inhibitor of tyrosine kinases DCC-2036 is effectiv...

Shen(Yingying),Shi(Xiaoke),Pan(Jingxuan) PLoS One 2014-04-16

...FIP1L1-PDGFRα-positive cells. DCC-2036 also exhibited in vivo antineoplastic activity against cells with T674I FIP1L1-PD...

A novel subtype of myeloproliferative disorder? JAK2V617F-associated hypereos...

Dasari(Sowjanya),Naha(Kushal),Hande(Manjun... BMJ Case Rep 2014-04-11

...FIP1L1-PDGFRA gene rearrangement, but positive for JAK2V617F mutation.

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