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Activated Microglia-Derived Extracellular Vesicles Elicit a Pro-Inflammatory As…

Scheld(M),Jülich(N),Vöhringer(K),Zendedel(A)… Biomolecules 2026-02-02

...Lcn2, Il-1β, Ccl2, Ccl5, Cxcl10) was quantified, and EV protein cargo was analyzed by mass spectrometry and proteomics. ...

Short-term vaginal prasterone therapy induces steroid receptor modulation and e…

Tomczyk(K),Yang-Jensen(KC),Lorentzen(LG),Chu… Sci Rep 2026-05-19

...LCN2, SERPINE2, and PRSS27, were downregulated. These findings indicate that short-term vaginal prasterone therapy promo...

Lipocalin-2 links spinal cord injury to neurogenic lung injury through MAPK/ERK…

Chen(Q),Wang(C),Wu(H),Xie(D),Niu(B),Yao(Q),L… Free Radic Biol Med 2026-05-00

...LCN2) in ASCI-induced lung injury and investigated the potential involvement of the LCN2/MAPK/ERK signaling axis in this...

Lipocalin 2 orchestrates resistance to ferroptosis via AXL.

Wang(SZ),Timken(JP),Hong(ES),Kaur(S),Newby(E… Cell Rep 2026-03-24

...LCN2) suppresses ferroptosis in GBM cells via the receptor tyrosine kinase AXL. LCN2 was elevated in GBM cells compared ...

Cross-Cohort Transcriptomic Integration Identifies IFIT2 as a Translational Dia…

Zhang(X),Chen(X),Yang(Y),Zhang(Y) Hum Mutat None

...LCN2) and inflammatory mediators (IL6 and CXCL10). Together, these results support IFIT2 as a promising candidate biomar...

N-acetylcysteine modulates neutrophil-driven immune and metabolic pathways in s…

Kang(J),Patil(D),Hackett(R),Cui(Y),Oza(K),Ru… Front Immunol None

...Lcn2), accompanied by the downregulation of lipid and cholesterol metabolism-related genes, including Cyp7a1, Cyp8b1, Cy...

Identification of Ferroptosis-Related Hub Genes Linked to Suppressed Sulfur Met…

Xu(Y),Xu(H),Ying(D),Wu(J),Wen(Y),Qiu(T),Ding… Pathogens 2026-01-23

...Lcn2, Timp1, Cth, Cp, Hmox1, Cbs, and Gclc) as key regulatory molecules. Functional enrichment analysis revealed that th...

Acinar Metaplastic Cells Generate Semi-Homogeneous Niches and Interact With Imm…

Arcila-Barrera(S),Yosefov-Levi(O),Shovman(Y)… Gastroenterology 2026-05-00

...Lcn2, and Cd274, highlighting genes that may drive the malignant process. In addition, we discovered niches that are hig...

Analysis of Antimicrobial Peptide Expression Under Acute and Chronic Alcohol Ex…

Rojas-Pirela(M),Herrera-Flores(C),Costa-Alba… Int J Mol Sci 2026-02-20

...LCN2, and LBP levels were markedly increased, whereas LL-37 and LEP1 were downregulated. Duodenal tissue exhibited upreg...

Pan-PPAR agonist bezafibrate alleviates psoriasis by suppressing LCN2-dependent…

Xin(R),Zhang(J),Zhang(Y),Dai(MP),Li(Y),Ma(JY… Free Radic Biol Med 2026-04-00

...LCN2 expression, and LCN2 overexpression abolished BEZ's protective effects against ferroptosis and inflammation in kera...

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