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Induction of human cardiomyocyte-like cells from fibroblasts by defined factors.

Wada(Rie),Muraoka(Naoto),Inagawa(Kohei),Ya... Proc Natl Acad Sci U S A 2013-11-26

...Myocd to GMT up-regulated a broader spectrum of cardiac genes in HCFs more efficiently compared with GMT alone. The HCFs...

Transplantation of mesenchymal cells rejuvenated by the overexpression of tel...

Madonna(Rosalinda),Taylor(Doris A),Geng(Yo... Circ Res 2013-11-07

...MYOCD or TERT. When compared with aged mock-transduced MSCs, aged MSCs overexpressing TERT, MYOCD, or both TERT and MYOC...

Myocardin and microRNA-1 modulate bladder activity through connexin 43 expres...

Imamura(Masaaki),Sugino(Yoshio),Long(Xiaoc... J Cell Physiol 2013-09-03

...MYOCD) and microRNA-1 (miR-1) in the regulation of connexin 43 (GJA1), a major gap junction in bladder smooth muscle, an...

Human embryonic stem cell derived mesenchymal progenitors express cardiac mar...

Raynaud(Christophe M),Halabi(Najeeb),Ellio... PLoS One 2013-08-02

...MYOCD. Nevertheless, NKX2-5+ hESC-MP derivatives did not form contractile cardiomyocytes, raising questions concerning t...

TSHZ3 and SOX9 regulate the timing of smooth muscle cell differentiation in t...

Martin(Elise),Caubit(Xavier),Airik(Rannar)... PLoS One 2013-12-17

...Myocd expression but significantly reduces the expression of MYOCD/SRF-dependent smooth muscle genes, suggesting that do...

Transcription factors MYOCD, SRF, Mesp1 and SMARCD3 enhance the cardio-induci...

Christoforou(Nicolas),Chellappan(Malathi),... PLoS One 2013-12-30

...MYOCD and SRF alone or in conjunction with Mesp1 and SMARCD3 enhanced the basal but necessary cardio-inducing effect of ...

down-regulation of Kruppel-like factor-4 (KLF4) by microRNA-143/145 is critic...

Davis-Dusenbery(Brandi N),Chan(Mun Chun),R... J Biol Chem 2012-05-11

...Myocd) or Myocd-related transcription factors (MRTFs). Krüppel-like factor-4 (KLF4) is known to inhibit activation of th...

Leiomodin 1, a new serum response factor-dependent target gene expressed pref...

Nanda(Vivek),Miano(Joseph M) J Biol Chem 2012-03-15

...MYOCD) transcriptional switch. Here, we describe a new SRF/MYOCD-dependent, SMC-restricted gene known as Leiomodin 1 (Lm...

Targeted gene-silencing reveals the functional significance of myocardin sign...

Torrado(Mario),Iglesias(Raquel),Centeno(Al... PLoS One 2012-02-24

...myocd but also myocd-dependent SM-marker genes are highly activated in failing left ventricular (LV) myocardium. In this...

In search of novel targets for heart disease: myocardin and myocardin-related...

Mikhailov(Alexander T),Torrado(Mario) Biochem Res Int 2012-08-23

...MYOCD) related family of transcriptional cofactors (MRTF-A and MRTF-B) which associate with the serum response transcrip...

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