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Identification of multigene predictors of prognosis in patients with ovarian ...

Liu(X),Chen(X),Jiang(L),Su(Y),Wang(C),Du(Z... iScience 2026-03-20

...PDGFRA were frequent among the top 20 OS models; 6 combinations predicted at least 50-month OS, and tissue microarray (1...

Multi-Omics Integration Identifies Key Pathways and Regulatory Genes Driving ...

Gao(L),Zhang(L),Chen(J),Peng(L),Zhang(S),Y... Animals (Basel) 2026-02-15

...PDGFRA, and FN1, were found to synergistically regulate marbling formation in YL cattle. This study systematically eluci...

Multi-omics reveals heterogeneity and functional populations of oligodendrocy...

Ye(D),Zhou(H),Qu(S),Wang(Z),Zhang(F),Wang(... Cell Death Discov 2026-03-02

...PDGFRA) expression. PDGFR-α+ hOPCs exhibited greater myelination, migration, and proliferation capabilities compared to ...

Lessons from Structural Biology for Understanding Drug Resistance in Gastroin...

Mancino(G),Schulz(T),Scrima(A),Müller(MP),... J Med Chem 2026-03-12

...PDGFRA. Targeted therapies have significantly improved patient outcomes; however, acquired drug resistance continues to ...

Navigating the complex landscape of duodenal gastrointestinal stromal tumor: ...

Xie(W),Hu(C),Luo(B),Cao(L),Zhong(Y),Liu(Y)... Crit Rev Oncol Hematol 2026-05-00

...PDGFRA mutation status, while emerging agents and ongoing clinical trials aim to address resistance and high-risk diseas...

Intimal sarcomas (ISarc) of the cardiac chambers (CC) of the heart and great ...

Zerdan(MB),Pavlick(D),Zaccarini(DJ),Ross(J... Cardiooncology 2026-02-28

...PDGFRA (53% CC, 42% GV), CDK4 (60% CC, 33% GV), and KIT (40% CC, 33% GV), though differences were not significant. CDKN2...

Disrupting MED8-dependent epigenetic reprogramming augments avapritinib sensi...

Xie(H),Xiong(Z),Huang(R),Dong(Y),Wang(Y),C... J Exp Clin Cancer Res 2026-05-19

PDGFRA genetic alterations are a well-established oncogenic driver in gliomas. However, targeted monotherapy against PDG...

cIMPACT-NOW update 12: Refining Pathology-based Risk Stratification and Gradi...

Brat(DJ),Aldape(K),French(PJ),Louis(DN),Na... Neuro Oncol 2026-05-18

...PDGFRA amplification was associated with highly aggressive clinical behavior of IDH-mutant astrocytomas, consistent with...

Genomic characterisation of Chinese myeloid malignancies and its clinical cor...

Liao(P),Xu(R),Geng(S),Deng(C),Huang(X),Wu(... Front Med (Lausanne) None

...PDGFRA, SETBP1, and KMT2C were associated with poorer prognosis in AML. In MDS, TP53 mutations, FAT1/ IL7R SNPs, and ele...

PDGF signaling regulates the adipocyte-to-fibroblast transition in wound heal...

Yao(L),Jeong(S),Bass(J),Kwon(HR),Olson(LE) Cell Rep 2026-06-23

...Pdgfra and Pdgfrb), while adipocytes express adiponectin (Adipoq). Here, we use two-step lineage tracing to label Pdgfra...

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