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Contributions of KRAS and RAL in non-small-cell lung cancer growth and progre...

Guin(Sunny),Ru(Yuanbin),Wynes(Murry W),Mis... J Thorac Oncol 2015-01-09

...RALA and RALB expression was associated with poor survival. In a panel of 14 human NSCLC cell lines, RALA and RALB had h...

Thermodynamic mapping of effector protein interfaces with RalA and RalB.

Campbell(Louise J),Peppa(Maria),Crabtree(M... Biochemistry 2015-04-08

...RalA and -B. Despite 100% sequence identity in the RalA and -B contact residues with RLIP76, differences still exist in ...

A rapid, membrane-dependent pathway directs furrow formation through RalA in ...

Holly(Ryan M),Mavor(Lauren M),Zuo(Zhongyua... Development 2015-09-21

...RalA) is required for fast furrow ingression in the early fly embryo. RalA function is absolutely required for furrow fo...

Genetic variations in angiopoietin and pericyte pathways and clinical outcome...

Stremitzer(Stefan),Zhang(Wu),Yang(Dongyun)... Cancer 2015-08-25

...RalA binding protein 1 [RALBP1]; and regulator of G-protein signaling 5 [RGS5]) were analyzed in samples of genomic DNA ...

Divergent roles of CAAX motif-signaled posttranslational modifications in the...

Gentry(Leanna R),Nishimura(Akiyuki),Cox(Ad... J Biol Chem 2015-12-04

...RalA protein. Finally, palmitoylation was critical for subcellular localization of RalB but not RalA. In summary, we hav...

Role for RalA downstream of Rac1 in skeletal muscle insulin signalling.

Takenaka(Nobuyuki),Sumi(Yukio),Matsuda(Kei... Biochem J 2015-11-10

...RalA. Notably, this RalA activation was remarkably impaired in rac1-deficient skeletal muscle fibres. Taken together, th...

The role of prostaglandin E2 in renal cell cancer development: future implica...

Kaminska(Katarzyna),Szczylik(Cezary),Lian(... Future Oncol 2015-08-05

...RalA signaling cascade in RCC cells. It also demonstrated upregulation of the expression of HIF-1α and PI3K/Akt/mTOR sig...

Mutant K-RAS Promotes Invasion and Metastasis in Pancreatic Cancer Through GT...

Padavano(Julianna),Henkhaus(Rebecca S),Che... Cancer Growth Metastasis 2015-10-29

...RalA) as key effector molecules, which control mutant K-RAS-dependent migration and invasion in MiaPaCa-2 cells. Our stu...

Spectroscopic studies of R(+)-α-lipoic acid--cyclodextrin complexes.

Ikuta(Naoko),Tanaka(Akira),Otsubo(Ayako),O... Int J Mol Sci 2015-07-13

...RALA) and S(-)-ALA (SALA). RALA is naturally occurring, and is a cofactor for mitochondrial enzymes, therefore playing a...

GARNL1, a major RalGAP α subunit in skeletal muscle, regulates insulin-stimul...

Chen(Qiaoli),Quan(Chao),Xie(Bingxian),Chen... Cell Signal 2015-01-06

...RalA activation and the RalA-dependent GLUT4 translocation in response to insulin in muscle cells. These findings show t...

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