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miR-128 and miR-149 enhance the chemosensitivity of temozolomide by Rap1B-med...

She(Xiaoling),Yu(Zhibin),Cui(Yulong),Lei(Q... Oncol Rep 2015-11-03

...Rap1B-mediated cytoskeletal and related molecular alterations. Moreover, miR-128 and miR-149 enhanced the chemosensitivi...

miR149 functions as a tumor suppressor by controlling breast epithelial cell ...

Bischoff(Annabell),Huck(Bettina),Keller(Be... Cancer Res 2015-01-20

...Rap1b, downstream of integrin receptors as miR149 targets, providing an explanation for the defective Src and Rac activa...

Albumin decrease is associated with spontaneous preterm delivery within 48 h ...

Heng(Yujing J),Taylor(Lorne),Larsen(Brett ... J Proteome Res 2015-12-07

...RAP1B, CAN1, IQGA2, ST1A1, COX5A, ADDA, and UBQL1) were significantly different between the two groups of women (p < 0.0...

Activation of Rap1 inhibits NADPH oxidase-dependent ROS generation in retinal...

Wang(Haibo),Jiang(Yanchao),Shi(Dallas),Qui... FASEB J 2014-02-26

...Rap1b, and activation of Rap1a by 8CPT in Rap1b(-/-) mice reduced laser-induced CNV, in correlation with decreased ROS g...

Longest neurite-specific activation of Rap1B in hippocampal neurons contribut...

Nakamura(Takeshi),Yasuda(Sayaka),Nagai(Hir... Genes Cells 2014-08-08

...Rap1B. Expression of Rap1B-G12V/E37G and G12V/Y40C mutants resulted in supernumerary axons. The targets of Rap1B-G12V/E3...

Rap1 GTPase activation and barrier enhancement in rpe inhibits choroidal neov...

Wittchen(Erika S),Nishimura(Eiichi),McClos... PLoS One 2014-06-15

...Rap1B isoforms is less clear. Compromise of retinal pigment epithelium barrier function is a contributing factor to the ...

Rap1 ameliorates renal tubular injury in diabetic nephropathy.

Xiao(Li),Zhu(Xuejing),Yang(Shikun),Liu(Fuy... Diabetes 2014-08-06

Rap1b ameliorates high glucose (HG)-induced mitochondrial dysfunction in tubular cells. However, its role and precise me...

Podocyte-specific RAP1GAP expression contributes to focal segmental glomerulo...

Potla(Uma),Ni(Jie),Vadaparampil(Justin),Ya... J Clin Invest 2014-06-02

...Rap1b induced massive glomerulosclerosis and premature death. Podocyte-specific Rap1a and Rap1b haploinsufficiency also ...

The chaperone protein SmgGDS interacts with small GTPases entering the prenyl...

Schuld(Nathan J),Vervacke(Jeffrey S),Lorim... J Biol Chem 2014-06-24

...Rap1B, we found that both SmgGDS-607 and SmgGDS-558 directly bind the GTPase C-terminal region, but the specificity of t...

miR-181 subunits enhance the chemosensitivity of temozolomide by Rap1B-mediat...

She(Xiaoling),Yu(Zhibin),Cui(Yulong),Lei(Q... Med Oncol 2014-10-22

...Rap1B-mediated cytoskeleton remodeling and related molecular (Cdc42, RhoA and N-cadherin) changes, suggesting that miR-1...

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