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[Molecular mechanisms underlying the pathology of Diamond-Blackfan anemia].

Toki(Tsutomu),Ito(Etsuro) Rinsho Ketsueki 2015-11-06

...RPL5, RPL11, RPL26 and RPL35A. These mutations have been reported in up to 60% of DBA patients. To date, no known pathog...

Mapping of the chromosomal amplification 1p21-22 in bladder cancer.

Scaravilli(Mauro),Asero(Paola),Tammela(Teu... BMC Res Notes 2015-04-14

...RPL5 and EVI5, showed significant overexpression in the SCaBER cell line compared to all the other samples tested. Oncom...

Clinical phenotype and genetic analysis of RPS19, RPL5, and RPL11 genes in Gr...

Delaporta(Polyxeni),Sofocleous(Christalena... Pediatr Blood Cancer 2015-02-04

...RPL5 gene (three patients). Mutations c.C390G (p.Y130X) and c.197_198insA (p.Y66X) detected in the RPL5 gene were novel....

Defects of protein production in erythroid cells revealed in a zebrafish Diam...

Zhang(Y),Ear(J),Yang(Z),Morimoto(K),Zhang(... Cell Death Dis 2015-06-04

...RPL5 have been reported. How ribosome protein deficiency causes defects specifically to red blood cells in DBA has not b...

SKIP and BIR-1/Survivin have potential to integrate proteome status with gene...

Kostrouch(David),Kostrouchová(Markéta),Yil... J Proteomics 2015-07-29

...RPL5, non-muscle myosin and TAC-1, a transcription cofactor and a centrosome associated protein. Together, these results...

Loss of function mutations in RPL27 and RPS27 identified by whole-exome seque...

Wang(RuNan),Yoshida(Kenichi),Toki(Tsutomu)... Br J Haematol 2015-05-14

...RPL5, RPL11, RPL26 and RPL35A as well as GATA1 in more than 50% of patients. However, the molecular aetiology of many Di...

A network of assembly factors is involved in remodeling rRNA elements during ...

Baßler(Jochen),Paternoga(Helge),Holdermann... J Cell Biol 2015-03-13

...Rpl5 and to ribosomal RNA (rRNA) helix 89 of the nascent peptidyl transferase center (PTC) through Nsa2. Importantly, Ns...

The role of IMP dehydrogenase 2 in Inauhzin-induced ribosomal stress.

Zhang(Qi),Zhou(Xiang),Wu(RuiZhi),Mosley(Am... Elife 2015-06-23

...RPL5, which inhibit MDM2 and activate p53. Inosine monophosphate (IMP) dehydrogenase 2 (IMPDH2) is a rate-limiting enzym...

Ribosomal proteins L11 and L5 activate TAp73 by overcoming MDM2 inhibition.

Zhou(X),Hao(Q),Zhang(Q),Liao(J-M),Ke(J-W),... Cell Death Differ 2015-12-24

...RPL5 and RPL11 can also enhance the transcriptional activity of a p53 homolog TAp73, but through a distinct mechanism. I...

5S ribosomal RNA is an essential component of a nascent ribosomal precursor c...

Donati(Giulio),Peddigari(Suresh),Mercer(Ca... Cell Rep 2014-01-31

...RPL5 or RPL11, did not induce p53. Instead, 5S rRNA acts in a dependent manner with RPL5 and RPL11 to inhibit Hdm2 and s...

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