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Effects of Huaier extract and autophagy factors on cholangiocarcinoma.

Yang(C),Wang(Y),Zhang(Y),Liu(Y),Wu(X) Medicine (Baltimore) 2025-07-18

...RPS6, AKT, and phosphorylated AKT protein levels. Similarly, in QBC939 cells, Huaier reduced viability, proliferation, m...

The SHFV nsp2 and nucleocapsid proteins recruit G3BP1 to sites of viral repli...

Lavender(AA),Solanke(O),Tang(H-Y),Peck(HE)... J Virol 2025-07-22

...rpS6), were redistributed into foci located in the same intracellular region as the viral dsRNA foci. However, SGs could...

Whey Protein Supplementation Combined with Exercise on Muscle Protein Synthes...

Ji(X),Ye(X),Ji(S),Zhang(S),Wang(Y),Zhou(Z)... Nutrients 2025-08-08

...rpS6) at 1-2 h post-exercise. Phosphorylation levels of p70S6K and rpS6 decreased 4-5 h after exercise. Conclusions: The...

Multi-omics profiling of metastatic colorectal cancer reveals the transcripti...

Jiang(Y),Li(Z),Zheng(F),Jia(W),Guo(Z),Xu(Z... Cancer Cell Int 2025-08-07

...RPS6 (p-RPS6) was the most differentially expressed protein between mCRC and nmCRC tumor tissues, which was found to be ...

MTOR signaling regulates the development of airway mucous cell metaplasia ass...

Kudrna(KM),Vilches(LF),Eilers(EM),Maurya(S... JCI Insight 2025-07-08

...RPS6 phosphorylation, which was reproduced using an IL-13-activated model of primary human airway epithelial cells (hAEC...

CARMIL2 deficiency disrupts activation-induced metabolic reprogramming in T c...

Kabha(M),Liaks-Bohnick(M),Zagairy(F),Atar(... J Allergy Clin Immunol 2025-11-00

...RPS6 phosphorylation, respectively, and upregulated the expression of IL17A in CARMIL2-mutated CD4+ T cells. CARMIL2 def...

Novel anticancer inhibitors targeting the PI3K/Akt/mTOR signaling route and a...

Yevale(D),Buha(V),Sangani(DU),Teraiya(N),S... Chem Biol Interact 2025-10-08

...RPS6 levels in Western blot, confirming PI3K/Akt/mTOR as the pathway of action. In addition, compound 6i stopped the cel...

Time-of-day effect of high-intensity muscle contraction on mTOR signaling and...

Mishima(T),Takenaka(Y),Hashimoto-Hachiya(A... Sci Rep 2025-07-03

...rpS6 during the light (sleep), than the dark (active) phase, while expression of the negative regulator of mTORC1 that r...

Development and application of a targeted phosphoproteomics method for analys...

Huwa(N),Schönenberger(R),Groh(KJ) J Proteomics 2025-08-15

...RPS6) of the mTOR pathway, which reflected transition from exponential growth to stationary subsistence. Our findings co...

Shared transcriptional regulators and network rewiring identify therapeutic t...

Norzagaray-Valenzuela(CD),Valdez-Flores(MA... Front Mol Biosci 2025-00-00

...RPS6 were central in HTN. Network rewiring analysis showed condition-specific changes in gene connectivity, particularly...

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