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Machine and Deep Learning Reveal Sequence Determinants Encoding Bivalent Histon…

Zhao(X),Wu(J),Che(Y),Long(C),Xing(Y),Li(H),Z… Commun Biol 2026-04-07

...SOX2, ESRRB, and TCFCP2l1. Deep learning models further improved predictive accuracy and uncovered motifs enriched at th...

Cancer-associated fibroblasts and immune escape-related genes serve as biologic…

Liu(X),Shi(A),Dai(B),Chang(Y),Yun(F),Guan(H)… Hereditas 2026-04-07

...SOX2, CXCL11, SPP1, APOE, and CXCL8) were screened. These genes are involved in the regulation of the immune response, c...

Dose-dependent biphasic effect of environmental UVA on stem cell function throu…

Zheng(Q),Ngo(HTT),Nguyen(TTM),Kim(JW),Choi(J… J Photochem Photobiol B 2026-05-00

...SOX2/OCT4 expression, and promoted chondrogenic potential. In contrast, doses of 0.5 J/cm2 or higher, particularly under...

Synthetic super-enhancers enable precision viral immunotherapy.

Koeber(U),Matjusaitis(M),Alfazema(N),Furlong… Nature 2026-05-00

...SOX2-driven and SOX9-driven transcriptional regulatory network in glioblastoma stem cells (GSCs)1, we engineered SSEs wi...

Transposable element-mediated evolutionary expansion of Sox2- and Brn2-binding …

Nishihara(H),Komiya(A) Genome Biol 2026-04-09

...Sox2 and Brn2, respectively. Epigenetics profiling suggests that approximately half of the Sox2- or Brn2-binding TEs fun...

Targeted elimination of CD44+ prostate cancer stem cells using hyaluronic acid-…

Vicil(S),Serttas(R),Erdogan(S) RSC Adv 2026-04-01

...SOX2, OCT3/4, NANOG). Intracellular ROS profiling further indicated redox modulation by SeNP-containing formulations, wi...

Exploring the molecular basis of microphthalmia and anophthalmia: Insights from…

Elmakkawy(G),Nabil(A),Nabil(K),Amin(AK),Mask… Mol Vis None

...SOX2, OTX2, CHD7, HMX1, PRR12, ATOH7, ZBTB11, B3GALNT2, GCNT2, DPH1, GJA8, FRAS1 and UBE3B. Among the variants, six were...

Enhancing reprogramming towards induced human expanded pluripotency through sub…

Hu(H),Ho(DHH),Yeung(SW),Tan(Y),Ho(SY),Weng(M… Commun Biol 2026-04-09

...SOX2 with engineered SOX17 transcription factors resulted in an approximately five-fold increase in the average yield of...

Direct glia-to-neuron conversion mitigates hippocampal damage in a vascular dem…

Ota-Elliott(RS),Fukui(Y),Hu(X),Bian(Y),Sun(H… J Cereb Blood Flow Metab 2026-04-11

...Sox2 (ANS), with the aim of assessing their therapeutic effects. Mice were sacrificed 2 months after ACAS surgery and ad...

Molecular and Cellular Analysis of Lipogems-Processed Lipoaspirates for Evaluat…

Al Sammarraie(SHA),Alessio(N),Aprile(D),Cast… Stem Cell Rev Rep 2026-07-00

...SOX2), and functional assays assessing proliferation, senescence, apoptosis, multilineage differentiation, IDO activity,...

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