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Modulation of interleukin-1 transcriptional response by the interaction betwe...

Blanco(Sandra),Sanz-García(Marta),Santos(C... PLoS One 2008-07-15

...VRK2 in response to interleukin-1beta. Also the reduction of endogenous VRK2 with shRNA increases the transcriptional re...

Vaccinia-related kinase 2 modulates the stress response to hypoxia mediated b...

Blanco(Sandra),Santos(Claudio),Lazo(Pedro ... Mol Cell Biol 2008-02-15

...VRK2). VRK2A is able to interact with TAK1 by its C-terminal region, forming stable complexes. The kinase activity of VR...

The vaccinia-related kinases phosphorylate the N' terminus of BAF, regulating...

Nichols(R Jeremy),Wiebe(Matthew S),Traktma... Mol Biol Cell 2006-08-08

...VRK2 efficiently phosphorylate the extreme N' terminus of the BAF protein (Barrier to Autointegration Factor). BAF binds...

Human cellular protein VRK2 interacts specifically with Epstein-Barr virus BH...

Li(Long-Yuan),Liu(Mei-Ying),Shih(Hsiu-Ming... J Gen Virol 2006-10-26

...VRK2) was isolated. Interaction between the cellular VRK2 and viral BHRF1 proteins was further demonstrated by glutathio...

The subcellular localization of vaccinia-related kinase-2 (VRK2) isoforms det...

Blanco(Sandra),Klimcakova(Lucia),Vega(Fran... FEBS J 2006-08-23

...VRK2B is detected in both the cytoplasm and the nucleus. VRK2A is expressed in all cell types, whereas VRK2B is expresse...

Characterization of three paralogous members of the Mammalian vaccinia relate...

Nichols(R Jeremy),Traktman(Paula) J Biol Chem 2004-05-03

...VRK2, and VRK3. We have annotated the gene structure for the members of this family and have characterized the enzyme ac...

Late onset of spermatogenesis and gain of fertility in POG-deficient mice ind...

Lu(Baisong),Bishop(Colin E) Biol Reprod 2004-04-06

...Vrk2 (vaccinia virus-related protein kinase 2). We have recently shown that like gcd/gcd mice, targeted Pog-/- males and...

Expression of the VRK (vaccinia-related kinase) gene family of p53 regulators...

Vega(Francisco M),Gonzalo(Pilar),Gaspar(Ma... FEBS Lett 2003-07-07

...VRK2 is expressed at lower levels than VRK1 and VRK3 in the mouse embryo. VRK genes play a role during embryonic develop...

Identification of two novel human putative serine/threonine kinases, VRK1 and...

Nezu(J),Oku(A),Jones(M H),Shimane(M) Genomics 1998-02-12

...VRK2. Comparison of VRK1 with VRK2 indicates that they encode structurally related putative Ser/Thr protein kinases. Nor...

VRK2 gene expression in schizophrenia, bipolar disorder and healthy controls.

Tesli(Martin),Wirgenes(Katrine Verena),Hug... Br J Psychiatry 0000-00-00

...VRK2) gene have been associated with schizophrenia, but the relevance of its encoded protein VRK2 in the disorder remain...

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