...Pgp substrates. To clarify whether Pgp is involved in the sensitizing effect of celecoxib, we investigated in vivo wheth...
...Pgp-expressing cells by virtue of modulation of Pgp-mediated transport. The synthetic taxane tRA96023 also modulates Pgp...
...Pgp relates in part to variance in drug transport capacity. In Pgp expressing cells, capacity for drug extrusion is gove...
...Pgp was found abnormally expressed on the plasma membrane of tumor cells with "classical" MDR phenotype. However, Pgp wa...
...Pgp) is an inducible transmembrane protein that functions as an ATP-dependent efflux pump. Pgp is normally expressed in ...
...Pgp blocker verapamil. Pgp expression was detected by immunocytochemistry in 14 out of 62 tumors (22.6%). No correlation...
...Pgp was collapsed by the addition of either the ATPase inhibitor, vanadate, or Pgp modulators. TMR transport by Pgp obey...
...Pgp correlates with the Pgp density. Vinblastine induces a conformational change in Pgp, evidenced by increased reactivi...
...Pgp)-mediated drug efflux to chemosensitize cancer cells at least as well or better than the Pgp modulator, cyclosporine...
...Pgp. These three transporters, and especially Pgp, are often targets of drugs. Pgp can be an intentional or unintentiona...
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