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Characterization of a guanine nucleotide-releasing factor and a GTPase-activa...

Burstein(E S),Macara(I G) Proc Natl Acad Sci U S A 1992-03-23

...rab3A. We have partially purified this activity, termed Rab3A-GRF, and a GTPase-activating protein (Rab3A-GAP) reported ...

Localization of the ras-like rab3A protein in the adult rat brain.

Moya(K L),Tavitian(B),Zahraoui(A),Tavitian(A) Brain Res 1992-12-15

Rab3A is a small GTP-binding synaptic vesicle protein, shown to dissociate from synaptic vesicle membranes upon depolari...

Expression of the ras-related rab3a gene in insulinoma-derived cell lines.

Lankat-Buttgereit(B),Göke(R),Fehmann(H C),... FEBS Lett 1992-12-07

This study was designed to search for the expression of the small-molecular-weight GTP-binding protein rab3a in endocrin...

Clathrin-coated vesicles in nervous tissue are involved primarily in synaptic...

Maycox(P R),Link(E),Reetz(A),Morris(S A),J... J Cell Biol 1992-10-14

...rab3A was absent, probably reflecting its dissociation from synaptic vesicles during endocytosis. Immunogold EM revealed...

Amino acid residues in the Ras-like GTPase Rab3A that specify sensitivity to ...

Burstein(E S),Brondyk(W H),Macara(I G) J Biol Chem 1992-12-16

...Rab3A to Rab3A-GRF and decreased the affinity of p25 Rab3A for Rab3A-GRF. Surprisingly, only one mutant in this region w...

Exocytotic fusion is activated by Rab3a peptides.

Oberhauser(A F),Monck(J R),Balch(W E),Fern... Nature 1992-12-16

...Rab3a, stimulate complete exocytotic degranulation, similar to that induced by GTP-gamma S. The response is selective fo...

GTP-binding mutants of rab1 and rab2 are potent inhibitors of vesicular trans...

Tisdale(E J),Bourne(J R),Khosravi-Far(R),D... J Cell Biol 1992-12-04

...rab3a, rab5, rab6, and H-ras did not inhibit processing of VSV-G to the complex, sialic acid containing form diagnostic ...

A synthetic peptide of the rab3a effector domain stimulates amylase release f...

Padfield(P J),Balch(W E),Jamieson(J D) Proc Natl Acad Sci U S A 1992-04-07

...rab3a effector domain, rab3AL, to examine whether a rab-like low molecular weight GTP-binding protein is involved in pro...

Specific expression of the ras-related rab3A gene in human normal and maligna...

Culine(S),Rousseau-Merck(M F),Honoré(N),Ne... Cancer 1992-12-01

...rab3A gene by Northern blot in 81 fresh tumors.,A high rab3A gene expression was observed in tumor samples derived from ...

Synaptic vesicle membrane proteins interact to form a multimeric complex.

Bennett(M K),Calakos(N),Kreiner(T),Schelle... J Cell Biol 1992-02-20

...rab3A, while solubilization of synaptic vesicles with Triton X-100 resulted in two predominant interactions, one involvi...

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