...hck) (Hck) and p58(c-fgr) (Fgr), members of the Src-family of protein tyrosine kinases, have been shown to be defective ...
...hck and lck, which belong to a family of structurally and functionally related effectors participating in signalling fro...
...hck-/-fgr-/-lyn-/- triple mutant cells, which are defective in spreading on fibronectin-coated surfaces in vitro and sho...
...Hck by the G-CSF-R in intact cells as well as in vitro. These studies revealed recruitment of Hck to activated G-CSF-R, ...
...Hck, and Yes were also expressed in the H526 cell line; only Yes showed a consistent increase in specific activity, whic...
...HCK gene expression, the genomic region containing the HCK promoter was isolated and functionally characterized. A DNA f...
...Hck and W260A Hck. The W260A mutant has a higher specific activity than wild type Hck. The W260A mutant requires autopho...
...Hck-SH3 interaction, as measured by surface-plasmon resonance, also abolished coprecipitation of NAK. As PAK family prot...
...Hck was activated and translocated to the phagosomal membrane, whereas in neutrophils engulfing mycobacteria, Hck did no...
...Hck molecules in the purified Hck preparation were not tyrosine-phosphorylated. In contrast to intact Hck, a recombinant...
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