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The antiepileptic drug topiramate is a substrate for human P-glycoprotein but n…

Luna-Tortós(C),Rambeck(B),Jürgens(UH),Lösche… Pharm Res 2009-11-00

...Pgp, MRP1, MRP2 or MRP5) to evaluate whether the AED topiramate is a substrate for any of these transporters. Known Pgp ...

In vitro flow cytometry method to quantitatively assess inhibitors of P-glycopr…

Wang(EJ),Casciano(CN),Clement(RP),Johnson(WW) Drug Metab Dispos 2000-05-00

...Pgp transporters, and is useful for screening or identifying inhibitors of Pgp as well as evaluation of potential for dr...

Expression and function of P-glycoprotein in a mouse kidney cell line.

Ernest(S),Bello-Reuss(E) Am J Physiol 1995-08-00

...PGP in proximal tubules and mesangium of mouse kidneys. A cell line (TKPTS) expressing PGP was developed from proximal t...

Impact of extracellular acidity on the activity of P-glycoprotein and the cytot…

Thews(O),Gassner(B),Kelleher(DK),Schwerdt(G)… Neoplasia 2006-02-00

...pGP activity was more than doubled after 3 to 6 hours of incubation in acidic medium, whereas cellular pGP expression re...

Reconstitution and functional studies of hamster P-glycoprotein in giant liposo…

Park(S),Majd(S) PLoS One 2018-00-00

...Pgp proteoliposomes to prepare giant Pgp-bearing liposomes via modified electroformation techniques. The presence of Pgp...

Aureobasidins: structure-activity relationships for the inhibition of the human…

Tiberghien(F),Kurome(T),Takesako(K),Didier(A… J Med Chem 2000-06-29

...Pgp function by the Pgp-mediated efflux of the calcein-AM Pgp substrate and uses human lymphoblastoid MDR-CEM (VBL(100))...

The association between pelvic girdle pain and pelvic floor muscle function in…

Fitzgerald(Colleen M),Mallinson(Trudy) Int Urogynecol J 2012-11-30

...PGP).,Fifty-five pregnant women with and without PGP were recruited in the second trimester who met inclusion for self-r...

Imaging multidrug resistance P-glycoprotein transport function using microPET w…

Bigott(HM),Prior(JL),Piwnica-Worms(DR),Welch… Mol Imaging 2005-00-00

...Pgp function. The reversal effect of a Pgp modulator was shown in tissue distribution studies of KB 3-1 (Pgp-) and KB 8-...

Pgp efflux pump decreases the cytostatic effect of CENP-E inhibitor GSK923295.

Tcherniuk(Sergey O),Oleinikov(Andrew V) Cancer Lett 2015-05-21

...Pgp could be more resistant to GSK923295, and that overexpression of Pgp can decrease the therapeutic effect of this dru...

Assessment of Malondialdehyde Belonging to Modulators and Substrates of the P-G…

Shchulkin(AV),Abalenikhina(YV),Mylnikov(PY),… Dokl Biochem Biophys 2022-12-00

...Pgp by acting through CAR and PXR, and MDA can be transported by Pgp. The induction of Pgp under the action of MDA durin...

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