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Attenuation of fibrosis in vitro and in vivo with SPARC siRNA.

Wang(Jiu-Cun),Lai(Syeling),Guo(Xinjian),Zh... Arthritis Res Ther 2010-09-23

...Col1a2 and the Ctgf were examined by real-time RT-PCR and Western blotting, respectively. In in vivo studies, C57BL/6 mi...

Cellular phenotype transformation occurs during thoracic aortic aneurysm deve...

Jones(Jeffrey A),Zavadzkas(Juozas A),Chang... J Thorac Cardiovasc Surg 2010-09-20

...Col1a2, Col3a1, Eln), and other matrix proteins, as well as decreased expression of Mmp3, Timp3, and Ltbp1. Moreover, ge...

Smad2 protects against TGF-beta/Smad3-mediated renal fibrosis.

Meng(Xiao Ming),Huang(Xiao Ru),Chung(Arthu... J Am Soc Nephrol 2010-09-23

...COL1A2). Moreover, deletion of Smad2 increased autoinduction of TGF-beta1. Conversely, overexpression of Smad2 attenuate...

Estradiol replacement alters expression of genes related to neurotransmission...

Sárvári(Miklós),Kalló(Imre),Hrabovszky(Eri... Endocrinology 2010-09-08

...Col1a2, Col3a1, Fmod, and Lum), and transcription (Irf7 and Nupr1). Seventy-four percent of the transcriptional changes ...

Prediction of epigenetically regulated genes in breast cancer cell lines.

Loss(Leandro A),Sadanandam(Anguraj),Durinc... BMC Bioinformatics 2010-10-13

...COL1A2, TOP2A, TFF1, and VAV3, genes whose key roles in epigenetic regulation is documented in the literature. Subnetwor...

Post-transcriptional up-regulation of Tsc-22 by Ybx1, a target of miR-216a, m...

Kato(Mitsuo),Wang(Lin),Putta(Sumanth),Wang... J Biol Chem 2010-11-16

...Col1a2) expression in MC through far upstream enhancer E-boxes by interaction of Tsc-22 with an E-box regulator, Tfe3. Y...

Switch from stress response to homeobox transcription factors in adipose tiss...

Dankel(Simon N),Fadnes(Dag J),Stavrum(Anne... PLoS One 2010-09-01

...COL1A2, COL3A1, COL5A1, COL6A3).,The data demonstrate a marked switch of transcription factors in adipose tissue after p...

Loss of beta1-integrin enhances TGF-beta1-induced collagen expression in epit...

Hayashida(Tomoko),Jones(Jonathan C R),Lee(... J Biol Chem 2010-10-26

...COL1A2 promoter activity in β1-k/d cells. Although αvβ3-integrin surface expression levels were not different, αvβ3-inte...

[Genetic basis for skeletal disease. Osteogenesis imperfecta and genetic abno...

Hasegawa(Kosei) Clin Calcium 2010-10-21

...COL1A2, other genes that concerns post-translational modification of type I collagen molecules such as CRTAP, LEPRE1, PP...

[Osteogenesis imperfecta and achievements in cell and gene therapy].

Marijanović(Inga),Radnić(Maja),Matić(Igor)... Acta Med Croatica 2010-10-28

...COL1A2 genes of type I collagen. There is no cure for OI and current treatments include surgical intervention, use of pr...

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