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Microtubule integrity regulates src-like and extracellular signal-regulated kin…

Schmid-Alliana(A),Menou(L),Manié(S),Schmid-A… J Biol Chem 1998-03-05

...Hck activities. The importance of Src kinases in the mediation of the colchicine effect is underscored by the fact that ...

Glycated human serum albumin induces IL-8 and MCP-1 gene expression in human co…

Bian(Z M),Elner(V M),Lukacs(N W),Strieter(R … Curr Eye Res 1998-03-11

...HCK) as compared to human umbilical vein endothelial cells (HUVEC), a model for vascular endothelial cells, after stimul...

Structures of Src-family tyrosine kinases.

Sicheri(F),Kuriyan(J) Curr Opin Struct Biol 1998-02-13

...Hck, containing the SH3, SH2 and catalytic domains, as well as a C-terminal regulatory tail, have been determined in the...

Resistance to endotoxic shock and reduced neutrophil migration in mice deficien…

Lowell(C A),Berton(G) Proc Natl Acad Sci U S A 1998-08-06

...hck) (Hck) and p58(c-fgr) (Fgr), members of the Src-family of protein tyrosine kinases, have been shown to be defective ...

Physical and functional association of the Src family kinases Fyn and Lyn with …

Ezumi(Y),Shindoh(K),Tsuji(M),Takayama(H) J Exp Med 1998-08-11

...Hck, and Lck, were physically associated with the GPVI-FcRgamma complex irrespective of stimulation. Furthermore, Fyn wa...

Nef proteins of distinct HIV-1 or -2 isolates differ in their binding propertie…

Karn(T),Hock(B),Holtrich(U),Adamski(M),Streb… Virology 1998-07-27

...HCK and LCK as well as serine/threonine kinases. We have confirmed the binding of HCK to HIV-1 subtype B Nef and demonst...

Downstream targets of urokinase-type plasminogen-activator-mediated signal tran…

Konakova(M),Hucho(F),Schleuning(W D) Eur J Biochem 1998-07-17

...hck and lck, which belong to a family of structurally and functionally related effectors participating in signalling fro...

A beta 1 integrin signaling pathway involving Src-family kinases, Cbl and PI-3 …

Meng(F),Lowell(C A) EMBO J 1998-09-22

...hck-/-fgr-/-lyn-/- triple mutant cells, which are defective in spreading on fibronectin-coated surfaces in vitro and sho...

Solution structure of the human Hck SH3 domain and identification of its ligand…

Horita(D A),Baldisseri(D M),Zhang(W),Altieri… J Mol Biol 1998-06-25

...Hck. Hck is involved in a number of cell signal transduction pathways, frequently in pathways associated with immune res...

Enhanced phosphorylation of Src family kinase substrates containing SH2 domain …

Pellicena(P),Stowell(K R),Miller(W T) J Biol Chem 1998-07-09

...Hck, but both orientations are utilized equally well by activated Hck. We discuss the possible implications of these res...

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