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Functional dissection of the mouse Hox-a5 gene.

Zhao(J J),Lazzarini(R A),Pick(L) EMBO J 1996-07-11

...Pbx1. Our results suggest that this type of protein-protein interaction may be essential for the biological activities o...

Structural determinants within Pbx1 that mediate cooperative DNA binding with p…

Lu(Q),Kamps(M P) Mol Cell Biol 1996-07-29

...Pbx1. In this study, we identify structural determinants of Pbx1 that are required for cooperative DNA binding with the ...

Pbx modulation of Hox homeodomain amino-terminal arms establishes different DNA…

Chang(C P),Brocchieri(L),Shen(W F),Largman(C… Mol Cell Biol 1996-07-29

...Pbx1 complexed with HoxA10, which lacks a hexapeptide but requires a conserved tryptophan-containing motif for cooperati...

A case of mature B-cell ALL with coexistence of t(1;19) and t(14;18) and expres…

Rowe(D),Devaraj(P E),Irving(J A),Hogarth(L),… Br J Haematol 1996-09-26

...PBX1 hybrid gene transcript. This translocation is very closely associated with a pre-B phenotype. t(14;18) is associate...

Pbx-1 Hox heterodimers bind DNA on inseparable half-sites that permit intrinsic…

Knoepfler(P S),Lu(Q),Kamps(M P) Nucleic Acids Res 1996-09-09

...Pbx1 core, and suggests that this T base is bound by both Pbx1 and Hox proteins, Pbx1 binding in the major grove and the...

TEL-AML1 fusion RNA as a new target to detect minimal residual disease in pedia…

Cayuela(J M),Baruchel(A),Orange(C),Madani(A)… Blood 1996-09-09

...PBX1, and MLL-AF4 transcripts were also studied by PCR in these cases. TEL-AML1 transcripts were found in 8 out of 35 (2...

Persistence of E2A/PBX1 transcripts in t(1;19) childhood acute lymphoblastic le…

Lanza(C),Gottardi(E),Gaidano(G),Vivenza(C),P… Leuk Res 1996-08-22

...PBX1 hybrid message in a panel of 37 consecutive childhood acute lymphoblastic leukemias (ALLs). Three patients with B-p...

Hox gene products modulate the DNA binding activity of Pbx1 and Pbx2.

van Dijk(M A),Peltenburg(L T),Murre(C) Mech Dev 1995-12-06

...Pbx1, Pbx2 and Pbx3. We show here that two members of this family, Pbx1 and Pbx2 bind cooperatively to DNA with both Hox...

Specific immunologic recognition of the tumor-specific E2A-PBX1 fusion-point an…

Berendes(P),Hoogeveen(A),van Dijk(M),van Den… Leukemia 1995-09-20

...PBX1 genes are fused, resulting in a chimeric E2A-PBX1 gene, encoding chimeric E2A-PBX1 proteins. As such, the amino aci...

Cooperative interactions between HOX and PBX proteins mediated by a conserved p…

Phelan(M L),Rambaldi(I),Featherstone(M S) Mol Cell Biol 1995-08-29

...PBX1A, participates in cooperative DNA binding with HOXA-1 and the Deformed group protein HOXD-4. Three Abdominal-B clas...

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