Arold(S),O'Brien(R),Franken(P),Strub(M P),Ho… Biochemistry 1998-11-18

...Hck SH3 to HIV-1 Nef show that the binding of Hck (KD = 1.5 microM) is approximately an order of magnitude tighter than ...

Sicheri(F),Moarefi(I),Kuriyan(J) Nature 1997-03-03

...Hck has been determined at 2.6/2.9 A resolution. Inhibition of enzymatic activity is a consequence of intramolecular int...

Moarefi(I),LaFevre-Bernt(M),Sicheri(F),Huse(… Nature 1997-03-03

...Hck SH3 domain, to either the downregulated or activated form of Hck causes a large increase in Hck catalytic activity. ...

Krump(E),Nikitas(K),Grinstein(S) J Biol Chem 1997-08-14

...hck) were phosphorylated and activated upon hypertonic challenge. We propose that cells respond to alterations in cell s...

Briggs(S D),Sharkey(M),Stevenson(M),Smithgal… J Biol Chem 1997-08-18

...Hck, a Src family member expressed primarily in myeloid cells. However, the effect of Nef on Hck activity in living cell...

Skubitz(K M),Campbell(K D),Skubitz(A P) J Immunol 1997-08-05

...hck and lyn were found to account for much of the tyrosine kinase activity associated with CD50 in neutrophils. The data...

Welch(H),Maridonneau-Parini(I) J Biol Chem 1997-02-18

...Hck is also weakly activated by fMet-Leu-Phe. Cell fractionation showed that opsonized zymosan and A23187 induce Hck act...

Anderson(S M),Burton(E A),Koch(B L) J Biol Chem 1997-02-12

...Hck, however, as binding of the Hck fusion protein to Cbl appeared to require multiple domains. The binding of the fusio...

De Franceschi(L),Fumagalli(L),Olivieri(O),Co… J Clin Invest 1997-02-24

...Hck play any role in erythrocyte function, we analyzed red cells isolated from fgr-/-, hck-/-, and fgr-/- hck-/- knock-o...

Crowley(M T),Costello(P S),Fitzer-Attas(C J)… J Exp Med 1997-11-13

...Hck, Fgr, and Lyn, exhibited poor Syk activation upon FcgammaR engagement, accompanied by a delay in FcgammaR-mediated p...