...Pgp expression and increased doxorubicin delivery to HT-29 cells, where it served as a substrate for Pgp, indicating the...
...PGP (PGP) and DSPE-PEG3400-cRGD (cRGD) were synthesized via michael addition reaction of maleimide (-Mal) with sulfhydry...
...PgP) nanoparticles (Rm-PgP) to enable localized and sustained drug delivery. In our previous findings, Rm-PgP administer...
...Pgp. With substitution of three residues of the pocket (Y307, Q725 and V982) with cysteine in a cysless Pgp, QZ59S-SSS, ...
...Pgp inhibition when the modulator is applied alone, decreased the EC50 of doxorubicin (DOX) in KB-V1 (Pgp+) cells in vit...
...Pgp-, and 124 (64%) were Pgp+. The median follow-up was 51 months. For Pgp+ patients, 5-year EFS after definitive surger...
...PGP is on chromosome 16. Family data suggest that PGP is not close to 16qh or alpha Hp. The most likely regional assignm...
PGP, as well as GPGPGP remain stable after 24-hour incubation in a proteolytic environment (in vitro), like equine and r...
...Pgp. In view of the absence of a generally recognized mechanism of action of Pgp, several existing models of the protein...
...Pgp and that resistance modulating agents targeting Pgp may be much less efficient in the clinic than in Pgp-expressing ...
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