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RT-PCR detection of mRNA recovered from archival glass slide smears.

Akoury(D A),Seo(J J),James(C D),Zaki(S R) Mod Pathol 1993-05-28

...PBX1 fusion cDNA was used in PCRs of RT cDNAs for each of the 23 specimens, three of which were pre-B-cell acute lymphob...

Detection and clinical relevance of genetic abnormalities in pediatric acute ly…

Izraeli(S),Janssen(J W),Haas(O A),Harbott(J)… Leukemia 1993-06-01

The E2A/PBX1 and the BCR/ABL fusion genes result from the t(1;19)(q23;p13) and the t(9;22)(q34;q11), respectively, and e...

New E2A/PBX1 fusion transcript in a patient with t(1;19)(q23;p13) acute lymphob…

Numata(S),Kato(K),Horibe(K) Leukemia 1993-10-08

...PBX1 gene on chromosome 1, leading to production of a fusion transcript. The fusion sites of the E2A and PBX1 coding seq...

Chimeric homeobox gene E2A-PBX1 induces proliferation, apoptosis, and malignant…

Dedera(D A),Waller(E K),LeBrun(D P),Sen-Maju… Cell 1993-10-15

Expression of the homeobox fusion gene E2A-PBX1 under control of the immunoglobulin heavy chain enhancer efficiently ind...

extradenticle, a regulator of homeotic gene activity, is a homolog of the homeo…

Rauskolb(C),Peifer(M),Wieschaus(E) Cell 1993-11-16

...Pbx1. exd is expressed during embryogenesis when the selector homeodomain proteins of the Antennapedia and bithorax comp...

E2A-Pbx1, the t(1;19) translocation protein of human pre-B-cell acute lymphocyt…

Kamps(M P),Baltimore(D) Mol Cell Biol 1993-01-27

...PBX1. To test the leukemic potential of this fused gene, a cDNA encoding its major protein product, p85E2A-Pbx1, was inc...

Human t(1;19)(q23;p13) pre-B acute lymphoblastic leukemia in mice with severe c…

Uckun(F M),Downing(J R),Gunther(R),Chelstrom… Blood 1993-07-01

...PBX1 fusion transcript positive t(1;19)(q23;p13) pre-B acute lymphoblastic leukemia (ALL). A marked variation existed in...

Dpbx, a new homeobox gene closely related to the human proto-oncogene pbx1 mole…

Flegel(W A),Singson(A W),Margolis(J S),Bang(… Mech Dev 1993-07-29

...pbx1, pbx2, and pbx3 has been described. pbx proteins are most closely related to two yeast regulatory proteins, a1 and ...

Molecular evidence of minimal residual disease after treatment for leukaemia an…

Potter(M N),Cross(N C),van Dongen(J J),Sagli… Leukemia 1993-09-10

...PBX1/E2A in t(1;19) acute lymphoblastic leukemia (ALL), or TAL-1 deletions in other T-ALLs. Comparable sensitivity may b...

Pbx1 is converted into a transcriptional activator upon acquiring the N-termina…

Van Dijk(M A),Voorhoeve(P M),Murre(C) Proc Natl Acad Sci U S A 1993-08-06

...Pbx1-binding sites are activated by the chimeric E2A-Pbx1 protein but not by Pbx1. These results indicate that the t(1;1...

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