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The CD4 determinant for downregulation by HIV-1 Nef directly binds to Nef. Mapp…

Grzesiek(S),Stahl(S J),Wingfield(P T),Bax(A) Biochemistry 1996-09-30

...Hck tyrosine protein kinase, the peptide binds to the same site on Nef but with slightly higher affinity (Kd approximate...

Analysis of CSK homologous kinase (CHK/HYL) in hematopoiesis by utilizing gene …

Hamaguchi(I),Yamaguchi(N),Suda(J),Iwama(A),H… Biochem Biophys Res Commun 1996-08-29

...Hck, and Fgr in cultured bone marrow cells, although CSK negatively regulates Src family kinases. These results suggest ...

[Immunohistochemical study of cytokeratin and vimentin expression in mixed type…

Yuasa(T) Nihon Sanka Fujinka Gakkai Za… 1996-12-24

...HCK) was positive in each acanthomatous component and only a small part of one adenocarcinomatous component. 3) In twelv...

Critical role of Lyn kinase in inhibition of neutrophil apoptosis by granulocyt…

Wei(S),Liu(J H),Epling-Burnette(P K),Gamero(… J Immunol 1996-12-27

...Hck, but not Fgr, tyrosine phosphorylation within 1 min. Co-immunoprecipitation studies indicated that only Lyn, but not...

CD63 associates with tyrosine kinase activity and CD11/CD18, and transmits an a…

Skubitz(K M),Campbell(K D),Iida(J),Skubitz(A… J Immunol 1996-12-17

...Hck accounted for much of the associated tyrosine kinase activity. The data suggest that CD63 Ab binding to the neutroph...

Activation of src-related tyrosine kinases by IL-3.

Anderson(S M),Jorgensen(B) J Immunol 1995-09-08

...hck, and lyn. While the overexpression of fyn, hck, or lyn in 32Dcl3 cells resulted in increased kinase activity and IL-...

Peptidoglycan induces transcription and secretion of TNF-alpha and activation o…

Gupta(D),Jin(Y P),Dziarski(R) J Immunol 1995-09-22

...hck, fgr, or vav) and increased the activities of mitogen-activated protein and rsk kinases. These PGN- and sPGN-induced...

Proline-rich (PxxP) motifs in HIV-1 Nef bind to SH3 domains of a subset of Src …

Saksela(K),Cheng(G),Baltimore(D) EMBO J 1995-03-17

...Hck and Lyn, but not to those of other tested Src family kinases or less related proteins. A unique cooperative role of ...

Immature B lymphocytes are deficient in expression of the src-family kinases p5…

Wechsler(R J),Monroe(J G) J Immunol 1995-02-27

...hck, and fyn; in addition, we find that they express significant amounts of the src-family kinase p55fgr. Immature B cel...

Myristoylation and differential palmitoylation of the HCK protein-tyrosine kina…

Robbins(S M),Quintrell(N A),Bishop(J M) Mol Cell Biol 1995-07-27

...HCK encodes two versions of a protein-tyrosine kinase, with molecular weights of 59,000 (p59hck) and 61,000 (p61hck). Th...

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