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Ultrastructural localization of PGP 9.5 and ubiquitin immunoreactivities in rat…

Martín(R),Santamaría(L),Fraile(B),Paniagua(R… Histochem J 1995-06-00

...PGP or ubiquitin. In the cauda epididymidis, immunostaining to PGP was observed in most clear cells and in isolated prin...

Kinetics of P-glycoprotein-mediated efflux of paclitaxel.

Jang(SH),Wientjes(MG),Au(JL) J Pharmacol Exp Ther 2001-09-00

...Pgp). The objective of the present study was to determine the kinetics of the Pgp-mediated efflux and its contribution t...

Vinca alkaloid binding to P-glycoprotein occurs in a processive manner.

Iqbal(S),Flux(C),Briggs(DA),Deplazes(E),Long… Biochim Biophys Acta Biomembr 2022-00-01

A mechanistic understanding of how P-glycoprotein (Pgp) is able to bind and transport its astonishing range of substrate...

Cross-Linking Mass Spectrometry on P-Glycoprotein.

Gellen(G),Klement(E),Biwott(K),Schlosser(G),… Int J Mol Sci 2023-06-25

...Pgp, and (ii) on-bead, subsequent to membrane preparation and immunoprecipitation. Pgp-containing complexes were enriche...

Do ATP-binding cassette transporters cause pharmacoresistance in epilepsy? Prob…

Löscher(W),Luna-Tortós(C),Römermann(K),Fedro… Curr Pharm Des 2011-00-00

...Pgp), the encoded product of the multidrug resistance- 1 (MDR1, ABCB1) gene. Pgp and MDR1 are markedly increased in epil...

A comparative small-animal PET evaluation of [11C]tariquidar, [11C]elacridar an…

Wanek(Thomas),Kuntner(Claudia),Bankstahl(Jen… Eur J Nucl Med Mol Imaging 2012-03-22

...Pgp). Pgp reduces intracellular concentrations of chemotherapeutic drugs. The aim of this study was to compare the suita...

Raltegravir does not revert efflux activity of MDR1-P-glycoprotein in human MDR…

Dupuis(Maria Luisa),Ascione(Alessandro),Palm… BMC Pharmacol Toxicol 2014-06-27

...Pgp).,Our study about RALT was performed by using a set of consolidated methodologies suitable for evaluating the MDR1-P...

Dual regulation of P-glycoprotein expression by trichostatin A in cancer cell l…

Balaguer(Trinidad Mata),Gómez-Martínez(Angel… BMC Mol Biol 2013-01-10

...Pgp mRNA produced in cell lines expressing Pgp protein. The different size of the Pgp mRNA is due to the use of alternat...

Correlation between steady-state ATP hydrolysis and vanadate-induced ADP trappi…

Kerr(KM),Sauna(ZE),Ambudkar(SV) J Biol Chem 2001-03-23

...Pgp. The ATPase activity of purified and reconstituted recombinant human Pgp was measured using a continuous cycling ass...

"Type III" cells of rat taste buds: immunohistochemical and ultrastructural stu…

Yee(CL),Yang(R),Böttger(B),Finger(TE),Kinnam… J Comp Neurol 2001-11-05

...PGP 9.5 and NSE always colocalize. In contrast, PGP 9.5 and serotonin seldom colocalize. Further, whereas the serotonin-...

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