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Brain distribution of cediranib is limited by active efflux at the blood-brai...

Wang(Tianli),Agarwal(Sagar),Elmquist(Willi... J Pharmacol Exp Ther 2012-08-20

...Bcrp1⁻/⁻ mice compared with wild-type and Bcrp1⁻/⁻ mice. Moreover, there was no significant difference in brain distribu...

Identification and characterization of a novel multipotent sub-population of ...

Takamiya(Michitaka),Haider(Khawaja H),Ashr... PLoS One 2012-03-05

...Bcrp1, Nestin, Musashi1 and Isl-1, and also showed differentiation into osteogenic, chondrogenic, smooth muscle, endothe...

Intestinal ciprofloxacin efflux: the role of breast cancer resistance protein...

Haslam(I S),Wright(J A),O'Reilly(D A),Sher... Drug Metab Dispos 2012-04-09

...bcrp1/BCRP-Madin-Darby canine kidney II (MDCKII) and multidrug resistance-related protein 4 (MRP4)-human embryonic kidne...

Acyclovir is a substrate for the human breast cancer resistance protein (BCRP...

Gunness(Patrina),Aleksa(Katarina),Koren(Gi... Can J Physiol Pharmacol 2012-02-08

...Bcrp1 (murine BCRP ortholog) mediates the transport of acyclovir into breast milk. It is plausible that acyclovir is als...

Bioavailability of the glucuronide and sulfate conjugates of genistein and da...

Álvarez(Ana I),Vallejo(Fernando),Barrera(B... Drug Metab Dispos 2012-05-02

...Bcrp1(-/-) mice after genistein administration (50 mg/kg b.wt.); 584.3 ± 90 in wild-type mice versus 4012 ± 612 in Bcrp1...

Modulation of the expression of ABC transporters in murine (J774) macrophages...

Vallet(Coralie M),Marquez(Béatrice),Nhiri(... Toxicology 2012-01-12

...Bcrp1), and a decreased expression of Abcc4 (Mrp4). While P-gp and Bcrp1 were functional, they did not modify the cellul...

The sulfated conjugate of biochanin A is a substrate of breast cancer resista...

An(Guohua),Morris(Marilyn E) Biopharm Drug Dispos 2012-02-07

...Bcrp1 cells. Genistein, an additional metabolite of biochanin A formed intracellularly, was also found to be a bcrp1 sub...

The gefitinib long-term responder (LTR)--a cancer stem-like cell story? Insig...

Gottschling(Sandra),Herpel(Esther),Eberhar... Lung Cancer 2012-09-24

...BCRP1 (breast cancer resistance protein 1). The results were compared to primary resistant patients (RPs) and intermedia...

Impact of P-glycoprotein (ABCB1) and breast cancer resistance protein (ABCG2)...

Mittapalli(Rajendar K),Vaidhyanathan(Shrut... J Pharmacol Exp Ther 2012-11-26

...Bcrp1(-/-) mice, and 1.00 ± 0.19 in Mdr1a/b(-/-)Bcrp1(-/-) mice compared with 0.012 ± 0.004 in wild-type mice. These dat...

Effects of per- and polyfluorinated compounds on adult rat testicular cells f...

Lindeman(Birgitte),Maass(Christine),Duale(... Reprod Toxicol 2012-10-15

...Bcrp1, Oat2 and P-gp were studied by real-time RT-PCR or flow cytometry. A PFNA associated increase in DNA SSBs was attr...

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