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Integrative machine learning reveals interplay between epithelial and endothe...

Zhang(S),Zheng(Y),Wang(J),Zhou(J),Li(Z),Zh... J Biomed Res 2026-05-25

...FLT1 axis, accompanied by increased expression of ESM1 and ANGPT2 in endothelial cells. Collectively, these findings sug...

Integrative Transcriptomic and Network Pharmacology Analysis Suggests Potenti...

Du(X),Zhu(J) Int J Womens Health 2026-00-00

...FLT1, and CD68). Expression validation and ROC curve analysis confirmed their significant dysregulation, with area under...

Identifying propionate metabolism-related genes as biomarkers of sepsis devel...

Yang(L),Shang(W),Chen(D),Qian(H),Zhang(S),... Sci Rep 2025-07-08

...FLT1 and VEGFB-FLT1, and the high propionate metabolism PCs and B cells might interact through BMP8B-BMPR2. Trajectory a...

Thrombospondin 2 drives liver metastasis in skin cutaneous melanoma via regul...

Zhang(LP),Zhang(ZG),Guan(J),Li(LQ) Melanoma Res 2025-10-01

...FLT1, MMP2, MMP9, and ECM components (LAMA4, COL1A1, and COL4A1) at mRNA and protein levels, inhibited melanoma cell mig...

Identification of transcription factors that regulate placental sFLT1 express...

Yong(Q),van der Keur(C),Anholts(JDH),Kapse... Mol Hum Reprod 2025-07-03

...FLT1. The identified TFs can serve as therapeutic targets in preeclampsia to keep the sFLT1 levels within appropriate li...

Microarray and Single-Cell RNA Sequencing Reveals G-Protein Gene Expression S...

Hashemi Karoii(D),Bavandi(S),Abroudi(AS),D... Stem Cell Rev Rep 2025-10-00

...FLT1, ADGRG6, CSF1R, IL7R, ADGRL3, OR4N4, MMD, SIRPB1, OR5I1, PTGDR, MPL, and GPR107 were up-regulated. Single-cell tran...

Delivery of Itgb1-siRNA by triptolide-modified and anti-Flt1 peptide-guided i...

Song(Y),Xu(T),Li(H),Liu(J),Cao(S),Yang(Y),... J Control Release 2025-07-10

...Flt1 in vascular endothelial cells and pericytes in CoNV using single-cell sequencing. Itgb1 knockdown significantly inh...

Mechanistic computational modeling of sFLT1 secretion dynamics.

Gill(A),Kinghorn(K),Bautch(VL),Mac Gabhann(F) PLoS Comput Biol 2025-08-00

...FLT1 (sFLT1 or sVEGFR1) binds and sequesters extracellular vascular endothelial growth factors (VEGF), thereby reducing ...

Placental network differences among obstetric syndromes identified with an in...

Piekos(SN),Barak(O),Baumgartner(A),Chu(T),... Commun Biol 2025-08-18

...FLT1, FSTL3, HTRA4, LEP, and PHYHIP), which distinguishes FGR + HDP placentas from those with other conditions, illustra...

FLT1 as a Protective Factor in Ischemic Stroke: Insights from Real-World Phar...

Chen(H),Yang(J),Li(Z),Gao(F) Transl Stroke Res 2025-12-00

...FLT1 was enriched in pathways such as MAPK and PI3K-Akt, implicated in stroke-related molecular processes. FLT1 was iden...

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