Chi(B),Zhang(Z),Zhang(Z),Zhang(H),Tian(M),Wa… Int J Mol Sci 2025-07-03

...GOT1 within this pathway was reversed by rhein. Furthermore, we found that the glutamine-aspartate-arginine metabolic pa...

Pourmandi(N),Jha(A),Muzzarelli(K),Lee(H),Ass… bioRxiv 2025-09-17

...GOT1. Follow-up thermal shift assays revealed that dAMP and dGMP destabilize GOT1 in the absence of its cofactor, pyrido...

Hodgetts(H),Martins(MC),Chen(L),Hall(AR),Luo… J Neuroendocrinol 2025-11-00

...GOT1 cells. GSEA data indicated ECM-related reactomes were downregulated in GOT1 cells grown in conditioned medium of LX...

Wu(XL),Lei(LP),Wu(SR),Chen(MY),Zhang(YQ),Fu(… Pathol Res Pract 2025-12-00

...GOT1 as key genes. GOT1 expression was downregulated in GC tissues with the lowest error value. Overexpression of GOT1 i...

Barazeghi(E),Backman(S),Hellman(P),Norlén(O)… Endocr Connect 2025-09-01

...GOT1, reduced cell growth and induced apoptosis, though cell migration remained unaffected. In addition, MBD2 expression...

Song(ZY),Yu(WJ),Jin(YJ),Zhou(MF),He(CX),Li(Z… J Ethnopharmacol 2025-09-25

...GOT1, GPT, and XDH as key targets associated with these metabolic disturbances. Molecular docking demonstrated strong bi...

Pareek(V),Benkovic(S) Nat Commun 2025-10-08

...GOT1 activity. While a low flux diffusive pathway generates the pathway intermediates in an accumulative process, it's t...

Li(T),Yan(Z),Zhou(M),Zhao(W),Zhang(F),Lv(S),… Pharmaceuticals (Basel) 2025-07-17

...GOT1), cytochrome P450 1A2 (CYP1A2), and carbonic anhydrase 2 (CA2). ScRNA-seq analysis indicated that HQD may enhance t...

Jang(Y),Ko(M),Lee(JY),Kim(JY),Lee(EW),Kwon(H… Autophagy 2025-12-00

...GOT1/AST: glutamic-oxaloacetic transaminase 1; GPT/ALT: glutamic-pyruvic transaminase; LAMP2: lysosomal associated membr...

Min(X),Du(Z),Wei(J),Yuan(Z),She(Y),Jin(X),Su… Exp Neurol 2025-11-00

...GOT1 modulate ferroptosis via its intrinsic enzymatic role: depletion of GOT1 substantially blocked the salvage synthesi...