Baruzzi(Anna),Remelli(Sabrina),Lorenzetto(Er… J Immunol 2016-02-26

...Hck and Fgr are required for Abl and Sos1 phosphorylation and Abl/Sos1 interaction in macrophages. Sos1 localizes to pod...

Ferrari(Silvia Martina),La Motta(Concettina)… Mini Rev Med Chem 2016-08-17

...Hck, lck, and fynT kinases, and a good inhibitor of c-Src and platelet-derived growth factor receptor) showed antineopla...

Shinya(Eiji),Shimizu(Masumi),Owaki(Atsuko),P… Virology 2016-04-25

...Hck) and p21-activated kinase 2 (PAK2), and that Hck, which is expressed strongly in iDCs, augmented this mutual interac...

Chen(Runzhe),Chen(Baoan) Drug Des Devel Ther 2016-05-17

...HCK, YES, FYN, FGR, BLK, LYN, FRK), as well as c-KIT, PDGFR-a and -b, and ephrin receptor kinase. Various clinical trial...

Musumeci(F),Schenone(S),Brullo(C),Desogus(A)… Curr Med Chem 2016-01-13

...Hck are involved in chronic myeloid leukemia and other hematologic tumors. Furthermore, Hck activity has been associated...

Goldman(Aaron),Majumder(Biswanath),Dhawan(An… Nat Commun 2016-02-01

...Hck) and suppression of apoptosis. The use of pharmacological inhibitors of SFK/Hck in combination with taxanes in a tem...

Kenney(Scott P),Meng(Xiang-Jin) Virus Res 2016-05-02

...Hck interaction. Both STAMI and Hck interactions with PRRSV N protein required an unhindered C-terminal domain as the in...

Makino(Yoshinori),Tsuda(Masumi),Ohba(Yusuke)… Cell Commun Signal 2016-03-08

...Hck directly phosphorylates ELMO1, regulating phagocytosis by promoting activation of Rac1; however, the involvement of ...

Biswas(Amlan),Shouval(Dror),Goettel(Jeremy),… Inflamm Bowel Dis 2016-06-10

...HCK, WAS), which were highly enriched in bone marrow derived macrophages (Mφ) and predicted to have a role in anti-infla...

Wan(Dan),Wang(Xu),Wu(Qinghua),Lin(Pingping),… Toxicol Sci 2016-07-19

...Hck) and EIF2AK2 transcriptions or use of chemical inhibitors of MAPK, p38, Ras, and JNK partially reversed the reductio...