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Differences in gene expression may contribute to the racial differences in th...

Gorlov(IP),Gorlova(OY),Thrift(AP) PLoS One None

...LEPR, ELOVL2, CD48, COL5A2, and ICAM1 in White individuals. Notably, divergence in gene expression profiles between raci...

A systematic literature review of economic evaluations of setmelanotide.

Belančić(A),Gkrinia(EMM),Sel(EK),Roncato(R... Eur J Clin Pharmacol 2026-04-20

...LEPR) deficiency. METHODS: The SLR was conducted according to PRISMA guidelines and registered on PROSPERO. Systematic s...

Genetic variants in the leptin-melanocortin pathway and their joint effects w...

Liang(X),Pan(S),Ji(J),Deng(Y),Chen(M),Huan... PLoS One None

...LEPR rs1137101, and POMC rs6713532. High unweighted GRS was associated with a higher obesity risk than low GRS (OR = 1.4...

Leptin-specific epigenetic modulation of preterm cord blood serves as a candi...

Boga(NS),Banerjee(AK),Varma(S),Molangiri(A... Pediatr Res 2026-05-15

...LEPR, IL6, and TNFα expression were increased in preterm cord blood (p < 0.05). Cord blood leptin levels were positively...

Exploring Autosomal Dominant Non-Syndromic Monogenic Obesity: From Genes to T...

Luppino(G),Giordano(M),Franchina(F),Coco(R... Curr Issues Mol Biol 2026-02-01

...LEPR, POMC, and PCSK1) or autosomal dominant (MC4R, SH2B1, SIM1, GNAS) modes of inheritance. Other gene mutations in het...

A Rat Model Investigation of Enhanced Facial Rejuvenation via PCL Microsphere...

Chu(PN),Zhu(S),Dai(X),Zhu(S) Aesthetic Plast Surg 2026-04-00

...LepR-positive PSCs was assessed. H&E and Masson's trichrome staining revealed significantly enhanced collagen ingrowth i...

Implantation awakens peri-implant osteogenic potential via Snx5-EGFR axis-med...

Jiang(X),Weng(Y),Feng(Y),Huang(J),Wang(H),... Int J Oral Sci 2026-02-20

...LepR+ MSCs and compromised implant-induced osteogenesis. Mechanistically, Snx5 facilitates the recycling of phosphorylat...

Chronic irregular photoperiod disrupts locomotor rhythms and hypothalamic clo...

Revueltas-Guillen(MF),Arellanes-Licea(EDC)... Chronobiol Int 2026-06-00

...Lepr). The irregular photoperiod differentially altered locomotor rhythms depending on phase delays or advances and incr...

A meta-analysis of potential genetic factors associated with antipsychotic-in...

Warner-Levy(J),Belston(L),Illangasekera(Y)... J Psychopharmacol 2026-04-00

...LEPR rs1137101 (GG + AG vs AA) Hedge's g 0.18 and CNR1 rs104935 (GG + AG vs AA), Hedge's g 0.55. The study identified si...

Marrow leptin-LEPR signaling rewires mitochondrial oxidative metabolism to co...

Liao(X),Dai(W),Xu(X),Cai(D),Tan(M),Wang(Z)... Cell Death Dis 2026-02-23

...LEPR antagonist Allo-aca restores chemosensitivity without altering baseline leukemia growth. Leptin up-regulates LEPR a...

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