Chen(Yumay),Chen(Phang-Lang),Chen(Chi-Fen)... Cell Cycle 2008-12-24

...Nek1. In Nek1(-/-) murine cells and in human cells with Nek1 expression silenced by siRNA, the checkpoint kinases Chk1 a...

Evangelista(Marie),Lim(Tze Yang),Lee(James... Sci Signal 2008-11-11

...Nek1 and Prkra did not directly function in the Hh pathway but exerted their effects on Hh signaling indirectly through ...

Rossi(Pellegrino),Lolicato(Francesca),Grim... Gene Expr Patterns 2008-04-02

...Nek1, Rnf141, Xrcc3, Tpo1, Tbca, Xrcc2, Mesp1, Phf7, Rtel1), whereas it down-regulates typical spermatogonial markers (f...

Pradel(Lydie C),Bonhivers(Mélanie),Landrei... J Cell Sci 2007-03-19

...NEK1 kinase domain (50%) but also shares 42% identity with human NEK2. TbNRKC is expressed in bloodstream and procyclic ...

Feige(Erez),Shalom(Ohad),Tsuriel(Shlomo),Y... Biochim Biophys Acta 2006-06-02

...Nek1 constructs suggests that the C-terminus of Nek1 bears cytoplasmic localization signal(s). Overexpression of nuclear...

Assmann(Eliana M),Alborghetti(Marcos R),Ca... J Biol Chem 2006-06-05

...NEK1, a protein kinase involved in polycystic kidney disease and DNA repair mechanisms at the G(2)/M phase of the cell c...

Mahjoub(Moe R),Trapp(Melissa L),Quarmby(Ly... J Am Soc Nephrol 2006-04-27

...Nek1 and Nek8 carry the causal mutations of two of the eight established mouse models of polycystic kidneys. Nek protein...

Quarmby(Lynne M),Mahjoub(Moe R) J Cell Sci 2006-02-21

...Nek1 and Nek8 have been linked with polycystic kidney disease. Results of statistical analysis indicate that the family ...

Polci(Rosaria),Peng(Aimin),Chen(Phang-Lang... Cancer Res 2005-02-03

...Nek1 have not been demonstrated to date. Here we show that Nek1 is involved early in the DNA damage response induced by ...

Mahjoub(Moe R),Qasim Rasi(M),Quarmby(Lynne M) Mol Biol Cell 2005-04-08

...Nek1 or Nek8 have cystic kidneys; therefore, our discovery that a member of this phylogenetic group of Nek proteins is l...