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Genome-wide association study of childhood B-cell acute lymphoblastic leukemia …

Im(C),Raduski(AR),Mills(LJ),Bhattarai(KR),Mo… Nat Commun 2025-10-22

...PBX1) and lower susceptibility for a subtype with excellent prognosis (ETV6-RUNX1). Functional experiments revealed nove...

Molecular genetic characteristics and clinical significance of childhood acute …

Zhu(Z),Yan(J) Front Pediatr 2025-00-00

...PBX1 and MLL showed about 50% consistency. The dynamic changes of MRD were closely related to gene types, with significa...

NKX6-3 in B-Cell Progenitor Differentiation and Leukemia.

Nagel(S),Meyer(C),Pommerenke(C) Genes (Basel) 2025-10-14

...PBX1, revealing a role for the HIPPO-pathway in B-cell progenitors and TCF3::PBX1-positive BCP-ALL. Collectively, our da...

Novel insights and clinical perception of the patients with acute leukemia tran…

Guo(Q),Liu(Y),Chen(X),Shen(J),Li(Z),Zeng(M),… Front Med (Lausanne) 2025-00-00

...PBX1 and DNMT3A were independent risk factors for mortality of ALL. Regardless of whether the subtype of AL patients inc...

Clinical characteristics and prognostic analysis of different fusion gene abnor…

Fan(R),Zhao(M),Li(P),Tian(Y),Liu(B),Zhu(X),C… Front Oncol 2025-00-00

...PBX1 (3.0%), MLL::AF4 (2.3%), other (1.5%) and SIL::TAL1 (0.8%). B-cell immunophenotype predominated (88.6%). E2A::PBX1-...

A Brief Review on the Role of the Transcription Factor PBX1 in Hematologic Mali…

Chatzileontiadou(S),Boulogeorgou(K),Frouzaki… Int J Mol Sci 2025-10-30

...PBX1 and its variant E2A::PBX1 regulate gene expression that influences cell proliferation and differentiation in hemato...

A rare PBX1 variant identified in adulthood: a case report.

Han(AR),Moon(Y),Kim(YG),Lee(SH),Moon(JY),Lim… Front Med (Lausanne) 2025-00-00

Abnormalities in PBX1 represent a monogenic cause of congenital anomalies of the kidney and urinary tract (CAKUT). Howev...

[A clinical and laboratory study of TCF3-PBX1 positive adult acute lymphoblasti…

Zheng(Ji-Fu),Qiu(Hui-Ying),Pan(Jin-Lan),Cen(… Zhonghua Xue Ye Xue Za Zhi 2016-04-23

To explore the morphology, immunophenotype, cytogenetics and clinical features of TCF3-PBX1 fusion gene positive adult a...

Associations of Polymorphisms in WNT9B and PBX1 with Mayer-Rokitansky-Küster-Ha…

Ma(Wenqing),Li(Ya),Wang(Man),Li(Haixia),Su(T… PLoS One 2016-05-04

...PBX1, WNT4, WNT7A, WNT9B, HOXA10, HOXA11, LHXA1 and GALT genes were genotyped using the Sequenom MassARRAY iPLEX platfor...

Clinical features and prognostic significance of TCF3-PBX1 fusion gene in Chine…

Pang(Li),Liang(Ying),Pan(Jian),Wang(Jian-Ron… Pediatr Hematol Oncol 2016-01-14

...PBX1 group. When intensive chemotherapy was used, the TCF3-PBX1 was associated with a favorable outcome in childhood pre...

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