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Role of P-glycoprotein in cyclosporine cytotoxicity in the cyclosporine-sirolim…

Anglicheau(D),Pallet(N),Rabant(M),Marquet(P)… Kidney Int 2006-10-17

...PGP-4008 were used as Pgp inhibitors. Rhodamine-123 (R-123), a fluorescent substrate of Pgp, was used to assess Pgp-medi...

Collagen degradation and neutrophilic infiltration: a vicious circle in inflamm…

Koelink(Pim J),Overbeek(Saskia A),Braber(Sas… Gut 2014-04-23

...PGP generation ex vivo. PGP levels were measured by mass spectrometry, and PGP neutralisation was achieved with a PGP an...

Angiotensin II inhibits P-glycoprotein in intestinal epithelial cells.

Kumar(A),Priyamvada(S),Soni(V),Anbazhagan(AN… Acta Physiol (Oxf) 2020-00-00

...Pgp is not known. Pgp activity was measured as verapamil-sensitive 3 H-digoxin flux. Pgp surface expression and exocytos...

Neuronal expression of the drug efflux transporter P-glycoprotein in the rat hi…

Volk(H A),Burkhardt(K),Potschka(H),Chen(J),B… Neuroscience 2004-03-31

...Pgp staining was confirmed by two different Pgp antibodies. Double immunolabeling and confocal microscopy showed that Pg...

2'[(18)F]-fluoroethylrhodamine B is a promising radiotracer to measure P-glycop…

Trencsényi(György),Kertész(István),Krasznai(… Eur J Pharm Sci 2016-02-11

...Pgp substrate character. ATPase assay as well as accumulation experiments carried out using Pgp(+) and Pgp(-) human gyne...

Drug-induced trafficking of p-glycoprotein in human brain capillary endothelial…

Noack(Andreas),Noack(Sandra),Hoffmann(Andrea… PLoS One 2014-09-26

...Pgp. Our data present the first direct evidence of drug-induced Pgp trafficking at the human BBB and indicate that Pgp h...

A cell-based high-throughput screen identifies inhibitors that overcome P-glyco…

Zahra(R),Furqan(M),Ullah(R),Mithani(A),Salee… PLoS One 2020-00-00

...Pgp was predicted through docking studies and both compounds inhibited Pgp in a biochemical assay. The inhibition of Pgp...

A CXCL8 receptor antagonist based on the structure of N-acetyl-proline-glycine-…

Jackson(Patricia L),Noerager(Brett D),Jablon… Eur J Pharmacol 2012-01-19

...PGP (NAc-L-Pro-Gly-L-Pro (LL-NAc-PGP), NAc-L-Pro-Gly-D-Pro (LD-NAc-PGP), NAc-D-Pro-Gly-L-Pro (DL-NAc-PGP), and NAc-D-Pro...

Effects of P-glycoprotein expression on cyclic AMP and volume-activated ion flu…

Kunzelmann(K),Slotki(I N),Klein(P),Koslowsky… J Cell Physiol 1994-12-27

...Pgp+ cells. Similarly, HCS increased Cl- conductance to the same extent in Pgp-, Pgp+ and Pgp-Rev cells. Verapamil (100 ...

Bap29varP, a variant of Bap29, influences the cell surface expression of the hu…

Rao(Prema S),Bickel(Ulrich),Srivenugopal(Kal… Int J Oncol 2008-03-20

...Pgp is targeted to the PM is not defined. To identify proteins that influence Pgp trafficking, we utilized the yeast two...

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