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Iterative, multimodal, and scalable single-cell profiling for discovery and c...

Blair(JD),Bradu(A),Dalgarno(C),Grabski(IN)... bioRxiv 2025-08-30

...RPS6 (pRPS6) as a case study. We present a customized workflow that uses the 10x Flex assay to jointly profile intracell...

RLX-201, a Novel mTORC1 Inhibitor With Potential to Promote Skin Longevity an...

Randhawa(M),Bojanowski(K),Ferraro(T),Huang... Dermatol Surg 2025-09-00

...RPS6 by immunocytochemistry and automated western blotting. RLX-201's effects on mTORC1 (p70S6K) and mTORC2 (pAKT Ser473...

Mammalian target of rapamycin pathway is up-regulated by both acute endurance...

Edgett(Brittany A),Fortner(Melanie L),Bone... Appl Physiol Nutr Metab 2016-04-22

...rpS6) mRNA was elevated (p < 0.05) at both 0 h (+32%) and 3 h (+47%). Both a catalytic subunit of eukaryotic initiation ...

Effect of early grain feeding of beef steers on postabsorptive metabolism.

Nayananjalie(W A D),Pike(K L),Wiles(T R),M... J Anim Sci 2016-05-03

...rpS6) and ribosomal protein S6 kinase 1 (S6K1) were significantly different during the early grain feeding period. Phosp...

Nutritional plane of twin-bearing ewes alters fetal mammary gland biochemical...

Sciascia(Q),Sales(F),van der Linden(D),War... J Anim Sci 2016-05-03

...RPS6)/RPS6 ( ≤ 0.05). Increased abundance of MAPK/mTOR pathway proteins is proposed to mediate increased protein synthet...

Regulation of the PI3K/AKT Pathway and Fuel Utilization During Primate Torpor...

Tessier(Shannon N),Zhang(Jing),Biggar(Kyle... Genomics Proteomics Bioinfo... 2016-02-12

...RPS6) in the heart, and a decrease in phospho-mammalian target of rapamycin (mTOR) in the kidney. Pyruvate dehydrogenase...

Lhx8 regulates primordial follicle activation and postnatal folliculogenesis.

Ren(Yu),Suzuki(Hitomi),Jagarlamudi(Krishna... BMC Biol 2016-04-05

...rpS6 activation. However, LHX8 does not directly regulate members of the PI3K-AKT pathway; instead, we show that LHX8 re...

Leucine and histidine independently regulate milk protein synthesis in bovine...

Gao(Hai-na),Hu(Han),Zheng(Nan),Wang(Jia-qi... J Zhejiang Univ Sci B 2016-03-04

...RPS6 (Ser(235/236)) at 5.40 to 10.80 mmol/L Leu all decreased. Similarly, the His supplementation from 0.15 to 9.60 mmol...

Immunohistochemical Assessment of Phosphorylated mTORC1-Pathway Proteins in H...

Harter(Patrick N),Jennewein(Lukas),Baumgar... PLoS One 2016-04-15

...RPS6-specific antibodies showed a reduced signal compared to controls. Staining intensity of both phospho-RPS6-specific ...

Alcohol intoxication following muscle contraction in mice decreases muscle pr...

Steiner(Jennifer L),Lang(Charles H) Alcohol Clin Exp Res 2016-05-19

...rpS6 Ser(240/244) , and 4E-BP1 Thr(37/46) ) and mitogen-activated protein kinase (MAPK) (JNK Thr(183) /Tyr(185) , p38 Th...

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