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Identification of drug candidates for rescue of SOX17 gene targets in pulmonary…

Vasilaki(E),Akosman(B),Song(S),Walters(R),Sh… bioRxiv 2026-05-18

...SOX17, we defined a robust SOX17 transcriptomic signature. In PAH patients, circulating plasma protein levels of 10 SOX1...

Transcriptional divergence of the zebrafish sox17 lineage begins during gastrul…

Tu(PS),Thompson(JD),Davalos(OA),Ligunas(GD),… bioRxiv 2026-06-29

...sox17 lineage, comprising endoderm and dorsal forerunner cells, throughout and immediately after gastrulation. We found ...

Identification of genomic features that uniquely impact estrogen receptor alpha…

Richey(A),Kitchen(N),Rush(CM),Vahrenkamp(JM)… bioRxiv 2026-06-29

...SOX17 in Ishikawa cells. In addition, the features that predict ER binding and effects on gene expression differ, with t...

Impaired SOX17 Expression Causes Endothelial Dysfunction and Pulmonary Arterial…

Akosman(B),Choi(MJ),Sharma(Y),Pereira(M),Lee… bioRxiv 2026-05-15

...SOX17 enhancer knockout (SOX17enhKO) mice, and Cdh5-CreERT2;Runx1(flox/flox);SOX17enhKO triple transgenic mice. SOX17 an...

Human biliary atresia extrahepatic cholangiocyte organoids express increased ER…

Har-Zahav(A),Hamoudi(Y),Danan(K),Tobar(A),Be… Front Bioeng Biotechnol None

...SOX17, and CFTR. ER stress markers PERK, BiP, and ATF4 were elevated, and TEM demonstrated abnormal ER morphology. Conve...

Endometrial Mesonephric-Like Carcinoma With Prominent Clear Cell Carcinoma-Like…

Valencia(MF),Protopsaltis(NJ),Song(W),Fadare… Int J Surg Pathol 2026-02-00

...SOX17, and calretinin (all negative), GATA3, and TTF1 (patchy positive). Diffuse immunoreactivity for CD10 and Napsin-A ...

Porcine iPSC-Derived Intestinal Cells as a High-Fidelity Platform for PEDV Path…

Muangthong(T),Chakritbudsabong(W),Taowan(J),… Animals (Basel) 2026-09-01

...SOX17 expression at day 5. By day 28, the piPSC-derived intestinal epithelial cells (piPSC-IECs) exhibited organized LGR...

SOX2 Is the Most Sensitive Biomarker in Testicular and Gynecologic Embryonic-ty…

Williams(JF),Glomski(K),Ulbright(TM),Hanley(… Am J Surg Pathol 2026-01-01

...SOX17, synaptophysin). Expression was evaluated for extent (0, negative; 1, ≤10% positive; 2, 11% to 50% positive; 3, >5...

Screening industrial chemicals for human developmental toxicity in the DevTox G…

Gamble(JT),Rogers(J),Breaux(K),Feshuk(M),Thu… Toxicology 2025-11-00

...SOX17 assay endpoint. For the test chemical set, 60 of the 165 chemicals analyzed were active, with 29 exhibiting a degr...

Molecular and Genetic Pathogenesis of Oral Cancer: A Basis for Customized Diagn…

Barroso(L),Veiga(P),Melo(JB),Carreira(IM),Ri… Biology (Basel) 2025-07-10

...SOX17, GATA4, ECAD, MGMT, and DAPK. Several microRNAs are upregulated in oral cancer, including miR-21, miR-24, miR-31, ...

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