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Curcumin alleviates the aggressiveness of breast cancer through inhibiting cell…

Li(M),Chen(L),Wang(M),Huang(X),Ke(Q),Hu(C) Biochem Pharmacol 2025-00-00

...TEAD4 shRNA (shTEAD4); Transcriptional coactivator with PDZ-binding motif (TAZ); TEA domain transcription factor 4 (TEAD...

A splicing isoform of TEAD4 attenuates the Hippo-YAP signalling to inhibit tumo…

Qi(Yangfan),Yu(Jing),Han(Wei),Fan(Xiaojuan),… Nat Commun 0000-00-00

...TEAD4-S, which lacks an N-terminal DNA-binding domain, but maintains YAP interaction domain. TEAD4-S is located in both ...

TEA domain transcription factor 4 modulates repression of fetal haemoglobin by …

Lin(J),Ye(Y),Shang(X),Zhang(Y),Wei(X),Xu(X) Br J Haematol 2021-12-00

...TEAD4 and HbF levels in β-thalassaemia patients. Functional validations of TEAD4 inhibition in both β-thalassaemia CD34+...

TEAD4: A key regulator of tumor metastasis and chemoresistance - Mechanisms and…

Liu(M),Hu(W),Meng(X),Wang(B) Biochim Biophys Acta Rev Canc… 2024-00-00

...TEAD4, a key mediator of the Hippo signaling pathway, has been implicated in regulating these factors that are all criti...

A cofactor-induced repressive type of transcription factor condensation can be …

Tang(Y),Chen(F),Fang(G),Zhang(H),Zhang(Y),Zh… EMBO J 2024-11-00

...TEAD4, that form condensates in stressed cells. In contrast to YAP-induced transcription-activating condensates of TEAD4...

TEAD4 ensures postimplantation development by promoting trophoblast self-renewa…

Saha(B),Ganguly(A),Home(P),Bhattacharya(B),R… Proc Natl Acad Sci U S A 2020-00-28

...TEAD4 is selectively expressed in trophoblast stem cell-like progenitor cells (TSPCs), and loss of Tead4 in postimplanta...

Reappraisal of psoriasis pathogenesis: the role of TEAD4 expression in keratino…

Shehata(WA),Hammam(MA),Elbakly(AR),Elkady(N) Int J Dermatol 2024-11-00

...TEAD4) is suggested to play a role in psoriasis development. TEAD4 expression in keratinocytes may have a chemotactic ef...

TEAD4 functions as a prognostic biomarker and triggers EMT via PI3K/AKT pathway…

Chi(M),Liu(J),Mei(C),Shi(Y),Liu(N),Jiang(X),… J Exp Clin Cancer Res 2022-05-17

...TEAD4 on tumor metastasis, we designed a metastatic nude-mouse model by tail vein injection of TEAD4-knockdown BLCA cell...

Generation of human embryonic stem cell lines (WAe001-A-67,WAe001-A-68) with TE…

Quan(Y),Jin(P),Ma(J),Yang(J),Wang(Z),Zhang(H… Stem Cell Res 2021-00-00

...TEAD4 in these processes. We generated TEAD1 and TEAD4 doxycycline-inducible expression human embryonic stem cell lines ...

Prognostic role of TEAD4 in TNBC: in-silico inhibition of the TEAD4-YAP interac…

Gupta(SRR),Singh(S),Rustagi(V),Pahuja(M),Man… In Silico Pharmacol 2024-00-00

...TEAD4-YAP interaction by binding to the YAP-binding domain of TEAD4. These findings underscore the significance of TEAD4...

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