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Peptidoglycan induces transcription and secretion of TNF-alpha and activation o…

Gupta(D),Jin(Y P),Dziarski(R) J Immunol 1995-09-22

...hck, fgr, or vav) and increased the activities of mitogen-activated protein and rsk kinases. These PGN- and sPGN-induced...

Molecular heterogeneity at the breakpoints of smaller 20q deletions.

Hollings(P E) Genes Chromosomes Cancer 1995-02-06

...HCK and the growth hormone releasing factor (GHRF) locus near the centromeric boundary of band 20q11.2. The distal break...

The Fc gamma RI receptor signals through the activation of hck and MAP kinase.

Durden(D L),Kim(H M),Calore(B),Liu(Y) J Immunol 1995-05-11

...hck, and cross-linking the Fc gamma RI receptor in U937IF cells results in the activation of hck kinase as evidenced by ...

Proline-rich sequences that bind to Src homology 3 domains with individual spec…

Alexandropoulos(K),Cheng(G),Baltimore(D) Proc Natl Acad Sci U S A 1995-05-25

...Hck bind to this sequence with the same affinity as that of the Src SH3. In contrast, a quite different proline-rich seq...

Myristoylation and differential palmitoylation of the HCK protein-tyrosine kina…

Robbins(S M),Quintrell(N A),Bishop(J M) Mol Cell Biol 1995-07-27

...HCK encodes two versions of a protein-tyrosine kinase, with molecular weights of 59,000 (p59hck) and 61,000 (p61hck). Th...

The Ras GTPase-activating protein (GAP) is an SH3 domain-binding protein and su…

Briggs(S D),Bryant(S S),Jove(R),Sanderson(S … J Biol Chem 1995-07-17

...Hck. GAP was present in WT Hck immunoprecipitates from the co-infected cells, indicative of Hck.GAP complex formation. U...

Distinct tyrosine kinase activation and Triton X-100 insolubility upon Fc gamma…

Zhou(M J),Lublin(D M),Link(D C),Brown(E J) J Biol Chem 1995-07-05

...Hck. In contrast, adhesion of PMN via Fc gamma RIIIB leads to activation and Triton X-100 insolubility of Hck but not Fg...

Signalling by the p60c-src family of protein-tyrosine kinases.

Kefalas(P),Brown(T R),Brickell(P M) Int J Biochem Cell Biol 1995-10-17

...hck, lck, lyn, c-src, c-yes and yrk), each encoding a cytoplasmic protein-tyrosine kinase (PTK) believed to be involved ...

CD66 family members are associated with tyrosine kinase activity in human neutr…

Skubitz(K M),Campbell(K D),Ahmed(K),Skubitz(… J Immunol 1995-12-28

...Hck accounted for much of the associated tyrosine kinase activity. The data suggest that phosphorylation of CD66a on tyr...

A single amino acid in the SH3 domain of Hck determines its high affinity and s…

Lee(C H),Leung(B),Lemmon(M A),Zheng(J),Cowbu… EMBO J 1995-12-21

...Hck SH3 with the highest affinity reported for an SH3-mediated interaction (KD 250 nM). In contrast to Hck, affinity of ...

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