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The immunolocalization of PGP 9.5 in normal human kidney and renal cell carcino…

D'Andrea(V),Malinovsky(L),Berni(A),Biancari(… G Chir 1997-10-00

...PGP 9.5. As PGP 9.5 is a marker of the diffuse endocrine system, the Authors believe that the stained cells of distal tu...

RNAi-mediated knockdown of P-glycoprotein using a transposon-based vector syste…

Rumpold(H),Wolf(AM),Gruenewald(K),Gastl(G),G… Exp Hematol 2005-07-00

...PgP in chronic myeloid leukemia cell lines resistant to imatinib and doxorubicin. Using this strategy, PgP expression wa...

Over-expression of multidrug resistance P-glycoprotein inhibits NK granule-medi…

N'cho(M),Hobbs(JA),Brahmi(Z) Hum Immunol 1999-03-00

...Pgp), the product of the MDR1 gene. In this study, we investigated whether over-expression of Pgp in natural killer (NK)...

Induction of apoptosis in MDR1 expressing cells by daunorubicin with combinatio…

Aszalos(A),Ladányi(A),Bocsi(J),Szende(B) Cancer Lett 2001-06-26

...Pgp modulators, which affect the function of Pgp by different mechanisms. Treatment of NIH3T3/MDR1 cells with combinatio...

Quantitative and functional assay of MDR1/P170-mediated MDR in ascites cells of…

Krasznai(ZT),Friedländer(E),Nagy(A),Szabó(G)… Anticancer Res 2005-00-00

...Pgp were detected by flow cytometry. For functional study, rhodamine 123 was used. Using the Pgp-specific UIC2 and MM6.1...

De novo prediction of p-glycoprotein-mediated efflux liability for druglike com…

Gunaydin(Hakan),Weiss(Matthew M),Sun(Yaxiong) ACS Med Chem Lett 2014-06-05

...Pgp) is capable of recognizing and transporting a wide range of chemically diverse compounds in vivo. Overcoming Pgp-med...

Assessment of Malondialdehyde Belonging to Modulators and Substrates of the P-G…

Shchulkin(AV),Abalenikhina(YV),Mylnikov(PY),… Dokl Biochem Biophys 2022-12-00

...Pgp by acting through CAR and PXR, and MDA can be transported by Pgp. The induction of Pgp under the action of MDA durin...

Prediction of P-glycoprotein inhibitors with machine learning classification mo…

Hinge(VK),Roy(D),Kovalenko(A) J Comput Aided Mol Des 2019-00-00

...PgP± (PgP inhibitors and non-inhibitors) compounds with the statistical-mechanical based three-dimensional reference int...

Importance of the difference in surface pressures of the cell membrane in doxor…

Bell(C),Hill(C),Burton(C),Blanchard(A),Sheph… Cell Biochem Biophys 2013-07-00

...Pgp) represents the archetypal mechanism of drug resistance. But Pgp alone cannot expel drugs. A small but growing body ...

Studying the Impact of Presence of Alpha Acid Glycoprotein and Protein Glycopro…

Al-Dewik(Nader I),Jewell(Andrew P),Yassin(Mo… Biomark Cancer 2015-12-07

...PGP levels and the resistance/response to treatment. A total of 26 CML patients were investigated for AGP and PGP levels...

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