The MDM2 protein plays an important role in the regulation of cell proliferation and apoptosis via ubiquitination and pr...
...Mdm2, pVHL, and BRCA1 have been linked to disease progression, prognosis, and resistance to drugs. Yet, there are hundre...
...MDM2-p53 binding interaction is a promising therapeutic strategy. Proof of concept was established with the cis-imidazol...
...mdm2-binding molecule restoring p53 function in the nucleus, and as a nucleophosmin-binding partner inside the nucleolou...
...mdm2, gadd45α, gadd45β, igfbp-3, and bax, were cloned from Chinese rare minnow (Gobiocypris rarus). These genes displaye...
...MDM2-dependent pathway or promoting apoptosis in a p53-independent manner. The ARF protein is mainly expressed in the nu...
...MDM2/p53 binding antagonists, these MDM2-amplified and TP53 mutant cell lines remained sensitive to ionizing radiation (...
...MDM2 impacts pluripotency and metabolism to promote survival and proliferation of cancer cells, independently of p53 deg...
...MDM2 has been considered the gold standard for diagnosis in these situations. Immunostaining for MDM2 and/or CDK4 has be...
...MDM2 expression was significantly reduced in exercised mice when compared with sedentary control. Meanwhile, p53 was sig...
联系地址
山东省济南市章丘区文博路2号
齐鲁师范学院 genelibs生信实验室
山东省济南市高新区舜华路750号
大学科技园北区F座4单元2楼
电话： 0531-88819269
版权所有 © 2025.Genelibs 济南弘晖生物技术有限公司 鲁ICP备20007159号-2
